ESTABLISHMENT AND DISTRIBUTION OF ACTINOMYCES-VISCOSUS AND ACTINOMYCES-NAESLUNDII IN HUMAN ORAL CAVITY
ESTABLISHMENT AND DISTRIBUTION OF ACTINOMYCES-VISCOSUS AND ACTINOMYCES-NAESLUNDII IN HUMAN ORAL CAVITY
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DOI：
10.1128/iai.14.5.1119-1124.1976
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发表时间：
1976-01-01
影响因子：
3.1
通讯作者：
ELLEN, RP
中科院分区：
文献类型：
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作者：
ELLEN, RP
使用最近开发的差异平板培养基 CNAC-20 研究了可疑牙周病原体粘性放线菌和内氏放线菌的口腔内建立和比例分布。采集了 108 名受试者（婴儿到年轻人）的唾液和牙菌斑样本；仅从成年受试者中采集舌头和颊粘膜样本。从 40% 的有齿前婴儿和几乎所有其他受试者的唾液样本中分离出过氧化氢酶阴性内氏放线菌。它在所有年龄段受试者的唾液、幼儿斑块和成人舌头样本中的 CNAC-20 分离株中占主导地位。相比之下，过氧化氢酶阳性的 A. viscous 并未从有齿婴儿样本中分离出来，并且其分离频率随着年龄的增长而缓慢增加（7 岁时检出率> 50%）。从牙菌斑和颊粘膜样品中分离出相对比例最高的 A. viscous。粘性放线菌和内氏放线菌这两个密切相关的物种在决定它们定殖的宿主年龄以及它们在人类口腔内的相对分布的因素方面明显不同。
The intraoral establishment and proportional distribution of suspected periodontal pathogens A. viscosus and A. naeslundii were studied using a recently developed differential plating medium, CNAC-20. Saliva and dental plaque samples were collected from 108 subjects (infants to young adults); tongue and buccal mucosa samples were collected from only the adult subjects. Catalase-negative A. naeslundii was isolated from 40% of the predentate infants'' and almost all other subjects'' saliva samples. It predominated among CNAC-20 isolates in the saliva of subjects of all age groups, in the plaques of young children, and in the adult tongue samples. In contrast, catalase-positive A. viscosus was not isolated from predentate infant samples, and its frequency of isolation increased slowly with age (> 50% detection by age 7). A. viscosus was isolated in highest relative proportions from dental plaque and buccal mucosa samples. The 2 closely related species A. viscosus and A. naeslundii apparently differ in respect to factors determining the host age at which they colonize and their relative intraoral distribution in humans.