A review on creatinine measurement techniques.
A review on creatinine measurement techniques.
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DOI：
10.1016/j.talanta.2012.04.005
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发表时间：
2012-08
期刊：
影响因子：
6.1
通讯作者：
Elham Mohabbati-Kalejahi;V. Azimirad;M. Bahrami;A. Ganbari
中科院分区：
文献类型：
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作者：
Elham Mohabbati-Kalejahi;V. Azimirad;M. Bahrami;A. Ganbari
本文综述了肌酐测定的全球最新趋势。肌酐生物传感器涉及生物和血液所受的微型机电一体化之间的复杂关系。新旧方法的比较表明，新技术(如基于分子印迹聚合物的算法)在稳定性和线性范围方面优于旧方法(如ELISA法)。对血清、血浆、尿液和血液样本的所有方法及其细节进行了综述。它们主要分为五种算法：光学法、电化学法、阻抗法、基于离子选择场效应晶体管(ISFET)的技术和层析。讨论了传感器的响应时间、检出限、线性范围和选择性。电位法的响应时间最短，为4-10s，最低检出限为0.28nmolL−-1，属于层析技术。对各种检测技术的比较表明，分子印迹聚合物和层析技术的选择性最好。
This paper reviews the entire recent global tendency for creatinine measurement. Creatinine biosensors involve complex relationships between biology and micro-mechatronics to which the blood is subjected. Comparison between new and old methods shows that new techniques (e.g. Molecular Imprinted Polymers based algorithms) are better than old methods (e.g. Elisa) in terms of stability and linear range. All methods and their details for serum, plasma, urine and blood samples are surveyed. They are categorized into five main algorithms: optical, electrochemical, impedometrical, Ion Selective Field-Effect Transistor (ISFET) based technique and chromatography. Response time, detection limit, linear range and selectivity of reported sensors are discussed. Potentiometric measurement technique has the lowest response time of 4–10s and the lowest detection limit of 0.28nmolL−1belongs to chromatographic technique. Comparison between various techniques of measurements indicates that the best selectivity belongs to MIP based and chromatographic techniques.