Risk of cancer with cyclosporine in psoriasis
Risk of cancer with cyclosporine in psoriasis
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DOI：
10.1046/j.1365-4362.36.s1.10.x
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发表时间：
1997-12-01
影响因子：
3.6
通讯作者：
Arellano, F
中科院分区：
文献类型：
--
作者：
Arellano, F
本文旨在确定环孢素相对于银屑病本身和其他治疗方法的风险。评估接受环孢素治疗牛皮癣的患者患癌症的风险是一项复杂的任务，涉及多个参数。在阳光照射较多的患者中，银屑病会更大程度地增加患皮肤癌的风险，不会增加患淋巴瘤的风险，并且通常只会轻微增加患癌症的风险。使用环孢菌素治疗似乎会增加患癌症的风险，其范围与其他免疫抑制剂大致相同。
The article aims to identify the risk of cyclosporine relative to that associated with psoriasis itself and with other treatments for the disease. Assessing the risk of cancer in patients receiving cyclosporine for psoriasis is a complex task that involves several parameters. Psoriasis increases the risk of skin cancer to a greater degree in patients with greater sun exposure, does not increase the risk of lymphoma, and increases the risk of cancers in general only slightly. Treatment with cyclosporine appears to increase the risk of cancer to approximately the same range as other immunosuppressants.