Degraded EEG Decoding of Wrist Movements in Absence of Kinaesthetic Feedback
Degraded EEG Decoding of Wrist Movements in Absence of Kinaesthetic Feedback
复制标题
DOI：
10.1002/hbm.22653
复制
发表时间：
2015-02-01
影响因子：
4.8
通讯作者：
Baker, Stuart N.
中科院分区：
文献类型：
--
作者：
Galan, Ferran;Baker, Mark R.;Baker, Stuart N.
脑机接口研究的一个主要假设是，神经通路断开的患者仍然可以随意回忆精确的运动命令，这些命令可以被解码，以进行自然的假肢控制。然而，这些患者的断开状态也阻碍了来自外周的动觉反馈，这已被证明调节负责准确运动控制的中央产生的输出。在这里，我们测试了在缺乏动觉反馈的情况下，通过解码三种情况下人类头皮脑电中的手部动作来生成运动指令的效果：未受损的运动、想象的运动和通过缺血神经阻滞暂时切断周围传入和传出神经时尝试的运动。我们的结果表明，在缺乏动觉反馈的情况下，皮质运动指令的回忆能力很差，这对精确的自然主义皮质假体控制的可能性提出了挑战。《哼唱大脑地图》36：643-654,2015。(C)2014年提交人。人类大脑图谱由威利期刊出版公司出版。
A major assumption of brain-machine interface research is that patients with disconnected neural pathways can still volitionally recall precise motor commands that could be decoded for naturalistic prosthetic control. However, the disconnected condition of these patients also blocks kinaesthetic feedback from the periphery, which has been shown to regulate centrally generated output responsible for accurate motor control. Here, we tested how well motor commands are generated in the absence of kinaesthetic feedback by decoding hand movements from human scalp electroencephalography in three conditions: unimpaired movement, imagined movement, and movement attempted during temporary disconnection of peripheral afferent and efferent nerves by ischemic nerve block. Our results suggest that the recall of cortical motor commands is impoverished in the absence of kinaesthetic feedback, challenging the possibility of precise naturalistic cortical prosthetic control. Hum Brain Mapp 36:643-654, 2015. (c) 2014 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc.