Leptinergic Regulation of Vertebrate Communication Signals
Leptinergic Regulation of Vertebrate Communication Signals
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脊椎动物通讯信号的瘦素能调节
DOI：
10.1093/icb/icab173
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发表时间：
2021
影响因子：
2.6
通讯作者：
Markham, Michael R
中科院分区：
文献类型：
--
作者：
Nourbakhsh-Rey, Mehrnoush;Markham, Michael R
动物交流信号由多个激素轴调节，以确保适当的信号目标，时间和信息内容。类固醇激素和许多肽激素的调节作用在广泛的脊椎动物分类群中得到了很好的理解和记录。最近的两项研究报道了瘦素的一种新功能，瘦素是一种对能量平衡调节至关重要的肽激素：调节弱电鱼类和唱歌小鼠的通信信号。目前只有有限的证据，一个关键问题是通信信号的瘦素调节在分类群内和分类群之间有多普遍。第二个重要的问题是什么样的通信信号的功能是受瘦素调节。在这里，我们考虑的功能意义的lepinergic调节动物的通信信号的背景下，直接和间接的信号代谢成本。直接成本来自于对信号产生的代谢投资，而间接成本来自于信号信息内容的捕食和社会冲突后果。我们提出了一个初步的概念框架，预测哪些物种将表现出瘦素调节他们的通信信号和信号功能瘦素将调节。这个框架提出了一些直接测试的预测内和跨类群。考虑到其他因素，如生活史和潜在的共同调节的通讯信号瘦素和糖皮质激素可能需要修改或阐述这个模型。
Animal communication signals are regulated by multiple hormonal axes that ensure appropriate signal targeting, timing, and information content. The regulatory roles of steroid hormones and many peptide hormones are well understood and documented across a wide range of vertebrate taxa. Two recent studies have reported a novel function for leptin, a peptide hormone central to energy balance regulation: regulating communication signals of weakly electric fish and singing mice. With only limited evidence available at this time, a key question is just how widespread leptinergic regulation of communication signals is within and across taxa. A second important question is what features of communication signals are subject to leptinergic regulation. Here, we consider the functional significance of leptinergic regulation of animal communication signals in the context of both direct and indirect signal metabolic costs. Direct costs arise from metabolic investment in signal production, while indirect costs arise from the predation and social conflict consequences of the signal's information content. We propose a preliminary conceptual framework for predicting which species will exhibit leptinergic regulation of their communication signals and which signal features leptin will regulate. This framework suggests a number of directly testable predictions within and across taxa. Accounting for additional factors such as life history and the potential co-regulation of communication signals by leptin and glucocorticoids will likely require modification or elaboration of this model.