Quality of Life in Pediatric Bipolar Disorder
Quality of Life in Pediatric Bipolar Disorder
复制标题
DOI：
10.1542/peds.2008-0841
复制
发表时间：
2009-03-01
期刊：
影响因子：
8
通讯作者：
Findling, Robert L.
中科院分区：
文献类型：
--
作者：
Freeman, Andrew J.;Youngstrom, Eric A.;Findling, Robert L.
OBJECTIVE.双相情感障碍是一种常见的心境障碍，与成人的严重残疾和生活质量受损相关。很少有研究探讨这种疾病对儿童和青少年生活质量的影响。目前的研究探讨了儿童和青少年双相情感障碍的生活质量与其他身体和精神疾病相比。这项研究包括529对青年和照顾者，他们在社区精神卫生中心或学术医疗中心寻求服务。诊断的基础上半结构化访谈的照顾者和青年，和生活质量是由父母报告的修订儿童生活质量问卷（KINDL）调查问卷，并与许多医疗疾病的公布基准进行比较。青年的平均年龄为12.0岁，57%为男孩，72%为黑人，22%为白色，17%接受过双相情感障碍诊断。与哮喘、特应性皮炎、肥胖、关节炎、氧依赖、婴儿期心脏手术、抑郁、行为障碍、非情绪和非行为精神病诊断相比，双相情感障碍青少年的生活质量评分显著降低。据报道，双相情感障碍的年轻人的生活质量低于儿科实践中遇到的其他年轻人。儿科医生不仅要注意孩子的情绪症状，还要注意这种疾病的整体损害。儿科2009; 123：e446-e452
OBJECTIVE. Bipolar disorder is a common mood disorder associated with significant disability and impairment in quality of life in adults. Little research has examined the impact of the disorder on quality of life in children and adolescents. The current study examines the quality of life in children and adolescents with bipolar disorder compared with other physical and psychiatric illnesses.METHODS. This study included 529 youth and caregiver pairs who sought services at a community mental health center or an academic medical center. Diagnoses were based on semistructured interviews of caregivers and youths, and quality of life was determined by the parent-reported Revised Children Quality of Life Questioinnaire (KINDL) questionnaire and compared with published benchmarks for many medical illnesses.RESULTS. Mean age of the youths was 12.0 years, 57% were boys, 72% were black, 22% were white, and 17% had received bipolar disorder diagnoses. Youths with bipolar disorder had significantly lower quality-of-life scores than youths with asthma, atopic dermatitis, obesity, arthritis, oxygen dependence, heart surgery during infancy, depression, behavior disorders, and nonmood and nonbehavior psychiatric diagnoses.CONCLUSIONS. Youths with bipolar disorder reported lower quality of life than other youths encountered in pediatric practice. Pediatricians should attend not only to the child's mood symptoms but also to the overall impairment of the disorder. Pediatrics 2009; 123: e446-e452