Psychomotor retardation and anhedonia in depression
Psychomotor retardation and anhedonia in depression
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DOI：
10.1111/j.1600-0447.1999.tb07221.x
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发表时间：
1999-04-01
影响因子：
6.7
通讯作者：
Winkler, T
中科院分区：
文献类型：
--
作者：
Lemke, MR;Puhl, P;Winkler, T
快感缺乏，无法体验快乐，以及观察到的精神运动表现的变化是重度抑郁症常见的精神病理现象，可能有共同的神经生物学机制。兴趣、愉悦和对愉悦刺激的反应性有助于运动的产生和可观察的行为。因此，我们对48例抑郁症患者进行了快感缺乏与精神运动发育迟缓的关系研究。主观经历的快感缺乏与自我评估的抑郁症相关，但与观察者评估的全球抑郁症严重程度无关。Widlocher智力发育迟缓评定量表评定的精神运动发育迟缓与快感缺乏显著相关。这些结果表明，在抑郁症患者中，体验快乐的能力降低与可观察到的精神运动发育迟缓之间存在经验关系。对精神运动现象的具体测量可能会进一步深入了解抑郁症中可观察到的行为和自我体验症状之间的关系。
Anhedonia, the inability to experience pleasure, and observed changes in psychomotor performance are frequent psychopathological phenomena in major depression with possible common neurobiological mechanisms. Interest, pleasure and reactivity to pleasurable stimuli contribute to movement generation and observable behaviour. Therefore the relationship between anhedonia and psychomotor retardation was studied in 48 depressed patients. Subjectively experienced anhedonia correlated with self-rated but not with observer-rated global severity of depression. There was a significant correlation between anhedonia and psychomotor retardation assessed with the Widlocher Retardation Scale. The results suggest the existence of an empirical relationship between reduced ability to experience pleasure and observable psychomotor retardation in depression. Specific measures of psychomotor phenomena may provide further insights into the relationship between observable behaviour and self-experienced symptoms in depression.