Growth process of small pancreatic carcinoma: A case report with imaging observation for 22 months

Growth process of small pancreatic carcinoma: A case report with imaging observation for 22 months
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DOI:
10.3748/wjg.14.1958
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发表时间:
2008-03-28
影响因子:
4.3
通讯作者:
Suda, Koichi
Suda, Koichi
中科院分区:
医学2区
文献类型:
--
作者:
Hisa, Takeshi;Ohkubo, Hiroki;Suda, Koichi

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This report describes serial observations of the growth process of a small invasive ductal carcinoma (IDC) of the pancreas from imaging studies. Histopathological studies showed IDC with macroscopic retention cysts proximal to an intraductal papillary-mucinous adenoma with mild atypia of the branch duct type in the pancreatic body, with no relation between the two lesions. IDC was demonstrated as an extremely low-echoic mass resembling a cyst with an unclear margin on the initial endoscopic ultrasonography. We misinterpreted the low-echoic mass as a benign intraductal mucinous-papillary neoplasm (IPMN) based on findings of other imaging studies, and the patient was followed-up. The mass increased from 7 mm to 13 mm in diameter over 22 mo, and remained smaller than 10 mm in diameter for about 420 d. The tumor volume doubling time was 252 d. The Ki67 labeling index was 15.9%, similar to that described in previous reports. Hence, IDC may grow slowly while remaining small. (c) 2008 WJG. All rights reserved.