NEURO-BEHAVIORAL DEFICITS AFTER LOW-LEVEL LEAD-EXPOSURE IN NEONATES - THE MEXICO-CITY PILOT-STUDY
NEURO-BEHAVIORAL DEFICITS AFTER LOW-LEVEL LEAD-EXPOSURE IN NEONATES - THE MEXICO-CITY PILOT-STUDY
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DOI：
10.1016/0892-0362(89)90046-9
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发表时间：
1989-03-01
影响因子：
2.9
通讯作者：
SVENDSGAARD, D
中科院分区：
文献类型：
--
作者：
ROTHENBERG, SJ;SCHNAAS, L;SVENDSGAARD, D
从怀孕36周到孩子出生，当母亲的血铅水平上升时，怀孕年龄和婴儿在生命的前30天内自我安静和得到安慰的能力就会下降。这些影响似乎与母亲和孩子的绝对铅水平无关（N = 42）。由于产前和围产期的压力预测更高的产妇出生铅，进一步的工作可以确定未被发现的压力在怀孕期间和铅水平升高后，随后的发展的相对贡献。几例未纳入统计分析的病例显示，脐带导联大大高于母体导联与不良结局之间存在相关性。
Gestation age and ability of the baby to self-quiet and to be consoled during the first 30 days of life decrease when mother''s blood lead levels rise from 36 weeks of pregnancy to birth of child. These effects appear to be independent of the absolute lead levels of mother and child (N = 42). Since pre- and perinatal stress predicts higher maternal birth lead, further work could determine the relative contributions of undetected stress during pregnancy and elevated lead levels upon subsequent development. Several cases, not included in the statistical analyses, showed associations between cord leads greatly elevated over maternal leads and poor outcome.