Colorectal Cancer Incidence Rates in the Louisiana Acadian Parishes Demonstrated to be Among the Highest in the United States
Colorectal Cancer Incidence Rates in the Louisiana Acadian Parishes Demonstrated to be Among the Highest in the United States
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DOI：
10.1038/ctg.2014.10
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发表时间：
2014-10-01
影响因子：
3.6
通讯作者：
Fontham, Elizabeth
中科院分区：
文献类型：
--
作者：
Karlitz, Jordan J.;Blanton, Christine;Fontham, Elizabeth
目的：确定结直肠癌（CRC）的发病率是否不成比例地高，在路易斯安那州的法国-拉丁美洲地区（人口120万），家的Cajuns，一个founder population.METHODS：2005 - 2009年癌症发病率分层的年龄/种族/性别在18拉丁美洲教区地区和9个教区亚组与较高比例的法语发言者，并与路易斯安那州和美国的利率。通过语言普查数据确定教区。共3,288例CRC病例被确定在路易斯安那州和路易斯安那州的11,737例。结果：在18个教区的白人和白色男性的CRC发病率在统计学上显著高于路易斯安那州和美国的发病率。在9个教区，发病率进一步上升;白人的发病率为56.1/10万，比路易斯安那州高13%（P
OBJECTIVES: Determine whether colorectal cancer (CRC) rates are disproportionately high in the French-Acadian region (population 1.2 million) of Louisiana, home of the Cajuns, a founder population.METHODS: 2005-2009 cancer incidence rates were stratified by age/race/gender in the 18 Acadian parish region and 9-parish subgroup with higher proportions of French speakers and compared with Louisiana and United States rates. Parishes were identified through language census data. A total of 3,288 CRC cases were identified in the Acadian region and 11,737 in Louisiana.RESULTS: CRC rates in whites and white males in the 18 parishes were statistically significantly higher than both Louisiana and US rates. In the 9 parishes, rates increased further; whites had an incidence of 56.1/100,000, 13% higher than Louisiana (P