Changing contextual factors from baseline to 9-months post-HIV diagnosis predict 5-year mortality in Durban, South Africa.
Changing contextual factors from baseline to 9-months post-HIV diagnosis predict 5-year mortality in Durban, South Africa.
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DOI：
10.1080/09540121.2020.1837338
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发表时间：
2021-12
期刊：
影响因子：
1.7
通讯作者：
Parker RA
中科院分区：
文献类型：
--
作者：
Bassett IV;Xu A;Giddy J;Bogart LM;Boulle A;Millham L;Losina E;Parker RA
Changes in an individual’s contextual factors following HIV diagnosis may influence long-term outcomes. We evaluated how changes to contextual factors between HIV diagnosis and 9-month follow-up predict 5-year mortality among HIV-infected individuals in Durban, South Africa enrolled in the Sizanani Trial (NCT01188941). We used random survival forests to identify 9-month variables and changes from baseline predictive of time to mortality. We incorporated these into a Cox proportional hazards model including age, sex, and starting ART by 9 months a priori, 9-month social support and competing needs, and changes in mental health between baseline and 9 months. Among 1,154 participants with South African ID numbers, 900 (78%) had baseline and 9-month data available of whom 109 (12%) died after 9-month follow up. Those who reported less social support at 9 months had a 16% higher risk of mortality. Participants who went without basic needs or healthcare at 9 months had a 2.6 times higher hazard of death compared to participants who did not. Low social support and competing needs at 9-month follow-up substantially increase long-term mortality risk. Reassessing contextual factors during follow-up and targeting interventions to increase social support and affordability of care may reduce long-term mortality for HIV-infected individuals in South Africa.
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影响因子：
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作者：
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通讯作者：
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DOI：
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发表时间：
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期刊：
The American psychologist
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1.7
作者：
Bogart LM;Chetty S;Giddy J;Sypek A;Sticklor L;Walensky RP;Losina E;Katz JN;Bassett IV
通讯作者：
Bassett IV
DOI：
10.1080/15381501.2017.1407732
发表时间：
2018
期刊：
Journal of HIV/AIDS & social services
影响因子：
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作者：
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