Hematopoietic Stem Cell Mobilization: Current Collection Approaches, Stem Cell Heterogeneity, and a Proposed New Method for Stem Cell Transplant Conditioning.
Hematopoietic Stem Cell Mobilization: Current Collection Approaches, Stem Cell Heterogeneity, and a Proposed New Method for Stem Cell Transplant Conditioning.
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DOI：
10.1007/s12015-021-10272-1
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发表时间：
2021-12
影响因子：
4.8
通讯作者：
Hoggatt J
中科院分区：
文献类型：
--
作者：
Menendez-Gonzalez JB;Hoggatt J
Hematopoietic stem cells naturally traffic out of their bone marrow niches into the peripheral blood. This natural trafficking process can be enhanced with numerous pharmacologic agents – a process termed “mobilization” – and the mobilized stem cells can be collected for transplantation. We review the current state of mobilization with an update on recent clinical trials and new biologic mechanisms regulating stem cell trafficking. We propose that hematopoietic mobilization can be used to answer questions regarding hematopoietic stem cell heterogeneity, can be used for non-toxic conditioning of patients receiving stem cell transplants, and can enhance gene editing and gene therapy strategies to cure genetic diseases.
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影响因子：
64.8
作者：
Adams, Gregor B.;Alley, Ian R.;Chung, Ung-il;Chabner, Karissa T.;Jeanson, Nathaniel T.;Lo Celso, Cristina;Marsters, Emily S.;Chen, Min;Weinstein, Lee S.;Lin, Charles P.;Kronenberg, Henry M.;Scadden, David T.
通讯作者：
Scadden, David T.
DOI：
10.1002/stem.2293
发表时间：
2016-04
期刊：
Stem cells (Dayton, Ohio)
影响因子：
--
作者：
Baba M;Toyama H;Sun L;Takubo K;Suh HC;Hasumi H;Nakamura-Ishizu A;Hasumi Y;Klarmann KD;Nakagata N;Schmidt LS;Linehan WM;Suda T;Keller JR
通讯作者：
Keller JR
影响因子：
20.3
作者：
Chen, J;Larochelle, A;Abkowitz, JL
通讯作者：
Abkowitz, JL
影响因子：
5.2
作者：
Barese, Cecilia;Pech, Nancy;Dinauer, Mary C.
通讯作者：
Dinauer, Mary C.
影响因子：
1.5
作者：
Ales, Tichopad;Veronika, Vitova;Daniel, Lysak
通讯作者：
Daniel, Lysak