A Fatality from an Oral Ingestion of Methamphetamine
A Fatality from an Oral Ingestion of Methamphetamine
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DOI：
10.1093/jat/33.8.557
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发表时间：
2009-10-01
影响因子：
2.5
通讯作者：
Marinetti, Laureen
中科院分区：
文献类型：
--
作者：
Kiely, Elizabeth;Lee, C. Jeff;Marinetti, Laureen
本病例是一名49岁白人男性死者，承认口服甲基苯丙胺。他认为，早上送女儿上学时，他被警察跟踪，吞下了“8球冰毒”，这种冰毒已知是1 / 8盎司，相当于约3克。通过气相色谱-质谱联用分析下列尸检标本的甲基苯丙胺和安非他明的存在：股血、尿、胆汁、玻璃体液、脑、肝和胃内容物。还分析了摄入后约12小时在医院抽取的血液。医院血液中甲基苯丙胺浓度为3.0 mg/L，尸检股骨血液中甲基苯丙胺浓度为30 mg/L。其他确认的药物包括曲马多、劳拉西泮和11-羧基-Δ9-tetrahydrocannabinol。病理学家判定死因是甲基苯丙胺药物作用导致的兴奋性谵妄引起的心律失常。讨论从摄入到死亡的时间线和死者的临床表现。
The case presented is of a 49-year-old white male decedent who admitted to oral ingestion of methamphetamine. He believed he was being followed by the police while walking his daughter to school in the morning and swallowed the “8-ball of meth,” which is known to be one-eighth of an ounce or the equivalent of about 3 g. The following autopsy specimens were analyzed for the presence of methamphetamine and amphetamine by gas chromatography-mass spectrometry: femoral blood, urine, bile, vitreous fluid, brain, liver, and gastric contents. Blood drawn at the hospital approximately 12 h after ingestion was also analyzed. The methamphetamine concentration in the hospital blood was 3.0 mg/L, and the concentration in the femoral blood from autopsy was 30 mg/L. Other drugs confirmed included tramadol, lorazepam, and 11-carboxy-Δ9-tetrahydrocannabinol. The pathologist ruled the cause of death to be cardiac dysrhythmia due to excited delirium as a result of methamphetamine drug effects. Discussion of the timeline from ingestion to death and the clinical presentation of the decedent are included.