Childhood Autism Rating Scale - Tokyo Version for screening pervasive developmental disorders
Childhood Autism Rating Scale - Tokyo Version for screening pervasive developmental disorders
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DOI：
10.1046/j.1440-1819.2003.01087.x
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发表时间：
2003-02-01
影响因子：
11.9
通讯作者：
Kurita, H
中科院分区：
文献类型：
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作者：
Tachimori, H;Osada, H;Kurita, H
为了评估儿童孤独症评定量表-东京版（CARS-TV）的效用，将其总分在430名患有DSM-IV的儿童中进行比较，每个亚组（即自闭症（AD）、儿童期分裂性障碍（CDD）、儿童期分裂性障碍和未另行说明的广泛性发育障碍（PDDNOS））。PDD组和非PDD精神发育迟滞（MR）组的Cronbach α值分别为0.91和0.89，两组合并为0.93。PDD组的总评分（平均值= 30.1，SD = 4.5）显著高于非PDD MR组（平均值= 22.9，SD = 3.3），t（503）= 13.7，P < 0.0001。区分PDD与非PDD MR的临界值为25.5/26，敏感性、特异性、阳性预测值和阴性预测值分别为0.86、0.83、0.97和0.50。4组间总分差异有统计学意义，其中CDD和AD组总分显著高于PDDNOS和Alzheimer病组，PDDNOS显著高于Alzheimer病组，CDD和AD组间差异无统计学意义。区分AD和PDDNOS的临界值为30/30.5，敏感性、特异性、阳性预测值和阴性预测值分别为0.71、0.75、0.77和0.69。CARS-TV似乎是区分PDD和非PDD MR以及AD和PDDNOS的有用工具，但需要进一步复制。
To assess the utility of the Childhood Autism Rating Scale - Tokyo Version (CARS-TV), its total score was compared among 430 children with DSM-IV per subgroup (i.e. autistic disorder (AD), childhood disintegrative disorder (CDD), Asperger's disorder, and pervasive developmental disorders (PDD) not otherwise specified (PDDNOS)). Values of Cronbach's alpha were 0.91 for the PDD group and 0.89 for the non-PDD mental retardation (MR) group, and 0.93 for both groups combined. The total score was significantly higher in PDD (mean = 30.1, SD = 4.5) than in non-PDD MR (mean = 22.9, SD = 3.3), t((503)) = 13.7, P < 0.0001. The cut-off to distinguish PDD from non-PDD MR was 25.5/26, with sensitivity, specificity, positive predictive value and negative predictive value of 0.86, 0.83, 0.97 and 0.50, respectively. The total score differed significantly among the four groups, with CDD and AD being significantly higher than both PDDNOS and Asperger's disorder, PDDNOS being significantly higher than Asperger's disorder and no significant difference between CDD and AD. The cut-off to distinguish AD from PDDNOS was 30/30.5, with sensitivity, specificity, positive predictive value and negative predictive value of 0.71, 0.75, 0.77 and 0.69, respectively. CARS-TV seems to be a useful instrument for differentiating between PDD and non-PDD MR and between AD and PDDNOS, although further replication is needed.