[Pronounced progression of interstitial pneumonia in a precious metal worker].
[Pronounced progression of interstitial pneumonia in a precious metal worker].
复制标题
[贵金属工人间质性肺炎的显着进展]。
DOI：
--
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Y. Kawabata
中科院分区：
文献类型：
--
作者：
K. Okabayashi;T. Yamaguchi;H. Amano;A. Nakagawa;T. Takao;M. Tamaki;T. Joh;Y. Murota;Y. Kawabata
一位从事贵金属加工业18年的43岁男性因劳累时呼吸急促而入院。胸部X线片显示右肺野和几乎所有左肺野的基底区有磨玻璃样阴影和环形结节影。进行了电视胸腔镜肺活检，组织学检查显示为普通型间质性肺炎（UIP）。矿物分析显示硅和铝的高模式，这两种元素与患者工厂中使用的材料一致。组织病理学结果表明，吸入粉尘颗粒引起的间质性肺炎。皮质类固醇治疗后，计算机断层扫描显示毛玻璃样阴影消退，但蜂窝状阴影仍然存在。2年前的胸部X线片显示右肺野基底区仅有微小的颗粒状病变。间质性阴影在2年的时间内显著进展。本研究结果对UIP的病因学研究有一定的参考价值。
A 43-year-old man who had been engaged in the precious-metal processing industry for 18 years was admitted to our hospital because of shortness of breath on exertion. Chest roentgenograms disclosed ground glass opacities and annular-nodular shadows in the basal area of the right lung field and almost all of the left lung field. A video-assisted thoracoscopic lung biopsy was performed, and histologic examination disclosed usual interstitial pneumonia (UIP). Mineral analysis revealed high modes of silicon and aluminum, two elements consistent with the materials used in the patient's factory. The histopathological findings indicated interstitial pneumonia caused by the inhalation of dust particles. After corticosteroid therapy, computed tomographic scans disclosed that the ground glass opacities had subsided, but that honeycomb shadows remained. A chest roentgenogram taken 2 years earlier demonstrated only minute granular lesions in the basal area of right lung field. The interstitial shadows had progressed significantly over the intervening 2-year span. The findings in this case should be of value to the etiologic study of UIP.