Effects of Achilles Tendon Immersion in Saline and Perfluorochemicals on T2 and T2*
Effects of Achilles Tendon Immersion in Saline and Perfluorochemicals on T2 and T2*
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DOI：
10.1002/jmri.24360
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发表时间：
2014-08-01
影响因子：
4.4
通讯作者：
Chung, Christine B.
中科院分区：
文献类型：
--
作者：
Chang, Eric Y.;Du, Jiang;Chung, Christine B.
目的：探讨不同溶液浸泡对跟腱的定性显示及对T2和T2*定量的影响。材料与方法：6只跟腱分别于基线空气中和生理盐水、Fomblin和全氟辛基溴(PFOB)中浸泡24 h后，在3T处进行解剖、切片(近端、中段和远端张力片)，对肌腱边界进行定性评价，定量计算Carr-Purcell-Meiom-Gill(CPMG)T2和超短回声时间(UTE)T2*。结果：在定性评价上，所有在空气中获得的图像都具有较大的空气组织敏感性效应。生理盐水组、Fomblin组和PFOB组空气中T2值分别为16.1+/-3.7、16.6+/-2.9和18.8+/-2.6ms，浸入液体后分别为14.8+/-4.6、15.9+/-3.0和17.7+/-3.0ms。生理盐水组、Fomblin组和PFOB组在空气中的平均T2*值分别为2.0+/-0.8、1.6+/-0.5和1.5+/-0.5ms，浸入液体后的平均T2*值分别为2.1+/-0.5、1.6+/-0.5和1.4+/-0.5ms。浸泡或液体类型对测量的T2或T2*没有显著影响(P&gT；0.1)。结论：这些结果证实了继续使用这些溶液可以防止肌腱标本脱水，并将敏感性影响降至最低。
Purpose: To determine if immersion of Achilles tendon segments into various solutions improved qualitative delineation of tendon and affected quantitative MR values of T2 and T2*.Materials and Methods: Six Achilles tendons were dissected, sectioned (proximal, midportion, and distal tensile pieces) and imaged at 3T both at baseline in air and after immersion into saline, Fomblin, and perfluorooctyl bromide (PFOB), respectively, for 24 h. Blinded readers qualitatively assessed the delineation of tendon boundaries and quantitatively Carr-Purcell-Meiboom-Gill (CPMG) T2 and ultrashort echo time (UTE) T2* was calculated. Comparison between images obtained in air and in solution was made.Results: On qualitative evaluation, all images obtained in air had larger air-tissue susceptibility effects. Mean T2 values of saline, Fomblin, and PFOB groups were 16.1 +/- 3.7, 16.6 +/- 2.9, and 18.8 +/- 2.6 ms at baseline in air, and 14.8 +/- 4.6, 15.9 +/- 3.0, and 17.7 +/- 3.0 ms after immersion in the fluid, respectively. Mean T2* values of saline, Fomblin, and PFOB groups were 2.0 +/- 0.8, 1.6 +/- 0.5, and 1.5 +/- 0.5 ms at baseline in air, and 2.1 +/- 0.5, 1.6 +/- 0.5, and 1.4 +/- 0.5 ms after immersion in the fluid, respectively. There was no significant effect of immersion or fluid type on measured T2 or T2* (P > 0.1).Conclusion: These results validate the continued use of these solutions to prevent tendon specimen dehydration and to minimize susceptibility effects.