Topology-Guided Multi-Class Cell Context Generation for Digital Pathology
Topology-Guided Multi-Class Cell Context Generation for Digital Pathology
复制标题
用于数字病理学的拓扑引导多类细胞上下文生成
DOI:
10.1109/cvpr52729.2023.00324
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发表时间:
2023
期刊:
影响因子:
--
通讯作者:
Chen, Chao
中科院分区:
文献类型:
--
作者:
Abousamra, Shahira;Gupta, Rajarsi;Kurc, Tahsin;Samaras, Dimitris;Saltz, Joel;Chen, Chao
In digital pathology, the spatial context of cells is important for cell classification, cancer diagnosis and prognosis. To model such complex cell context, however, is challenging. Cells form different mixtures, lineages, clusters and holes. To model such structural patterns in a learnable fashion, we introduce several mathematical tools from spatial statistics and topological data analysis. We incorporate such structural descriptors into a deep generative model as both conditional inputs and a differentiable loss. This way, we are able to generate high quality multi-class cell layouts for the first time. We show that the topology-rich cell layouts can be used for data augmentation and improve the performance of downstream tasks such as cell classification.
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DOI:
--
发表时间:
2019
期刊:
bioRxiv
影响因子:
--
作者:
Safoora Yousefi;Yao Nie
通讯作者:
Yao Nie
DOI:
10.1016/j.juro.2009.08.026
发表时间:
2009-12
期刊:
The Journal of urology
影响因子:
--
作者:
Wright JL;Salinas CA;Lin DW;Kolb S;Koopmeiners J;Feng Z;Stanford JL
通讯作者:
Stanford JL
影响因子:
8.8
作者:
Saltz J;Gupta R;Hou L;Kurc T;Singh P;Nguyen V;Samaras D;Shroyer KR;Zhao T;Batiste R;Van Arnam J;Cancer Genome Atlas Research Network;Shmulevich I;Rao AUK;Lazar AJ;Sharma A;Thorsson V
通讯作者:
Thorsson V
DOI:
10.1109/isbi53787.2023.10230507
发表时间:
2022-09
期刊:
2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)
影响因子:
--
作者:
Haotian Wang;Min Xian;Aleksandar Vakanski;Bryar Shareef
通讯作者:
Haotian Wang;Min Xian;Aleksandar Vakanski;Bryar Shareef
DOI:
--
发表时间:
2019
期刊:
Proceedings of Machine Learning Research
影响因子:
--
作者:
Wu, P.;Huang, Q.;Yi, J.;Riedlinger, G. M.;De, S.;Metaxas, D.
通讯作者:
Metaxas, D.