Effects of a long-term aerobic exercise intervention on institutionalized patients with dementia
Effects of a long-term aerobic exercise intervention on institutionalized patients with dementia
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DOI：
10.1016/j.jsams.2015.05.007
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发表时间：
2016-04-01
影响因子：
4
通讯作者：
Seijo, Manuel
中科院分区：
文献类型：
--
作者：
Cancela, Jose M.;Ayan, Carlos;Seijo, Manuel
目的：旨在分析体育锻炼对住院痴呆症患者重要健康指标影响的长期干预措施相对较少。这项纵向研究旨在确定体育锻炼计划对住院痴呆患者认知衰退、记忆、抑郁、功能依赖和神经精神障碍的影响。设计：随机对照试验。方法：将居家护理人员分配到痴呆症患者锻炼组(EG)或对照组(CG)。在15个月的时间里，实验组的参与者每天至少骑自行车15分钟，而对照组的参与者则进行替代的久坐娱乐活动。干预前后分别进行简易智力状态检查(MEC)、计时“起来”测验、神经精神病学问卷、Katz指数、康奈尔痴呆抑郁量表和Fuld物体记忆评定。结果：对照组63人和实验组51人完成干预。在包括在CG中的个体中，观察到认知功能显著下降(p=0.015)，而在包括在EG中的个体中，观察到轻微的改善。在那些锻炼的人中，观察到神经精神症状(p=0.020)、记忆功能(p=0.028)和功能活动(p=0.043)显著改善。结论：本研究提供的证据表明，有氧体育锻炼对改善住院痴呆症患者的认知功能、行为和功能活动能力有显著影响。(C)2015年澳大利亚运动医学。爱思唯尔有限公司出版。保留所有权利。
Objectives: Long-term interventions aimed at analyzing the impact of physical exercise on important health markers in institutionalized individuals with dementia are relatively scarce. This longitudinal study intends to identify the effects of a physical exercise program on cognitive decline, memory, depression, functional dependence and neuropsychiatric disturbances in institutionalized individuals with dementia.Design: Randomized controlled trial.Methods: Homecare residents with dementia were assigned to an exercise (EG) or to a control group (CG). Participants in the EG cycled for at least 15 min daily during 15 months, while those in the CG performed alternative sedentary recreational activities. The Mini-Mental State Examination (MEC), the Timed "Up & Go" Test, the Neuropsychiatric Inventory, the Katz Index, the Cornell Scale for Depression in Dementia and the Fuld Object Memory Evaluation were administered before and after the intervention.Results: Sixty-three individuals in the CG and 51 individuals in the EG completed the intervention. A statistically significant decline in cognitive function was observed in individuals included in the CG (p = 0.015), while a slight improvement was observed in those included in the EG. Significant improvement was observed in the neuropsychiatric symptoms (p = 0.020), memory function (p = 0.028) and functional mobility (p = 0.043) among those who exercised. Exercise seemed to have a greater effect in those suffering from severe cognitive impairment.Conclusions: This study provides evidence that aerobic physical exercise has a significant impact on improving cognitive functioning, behavior, and functional mobility in institutionalized individuals with dementia. (C) 2015 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.