OBSERVATIONS ON CRYSTALS FOUND IN INTESTINE OF NEMATODIRUS-BATTUS DURING DEVELOPMENT OF IMMUNITY TO THIS NEMATODE IN LAMBS
OBSERVATIONS ON CRYSTALS FOUND IN INTESTINE OF NEMATODIRUS-BATTUS DURING DEVELOPMENT OF IMMUNITY TO THIS NEMATODE IN LAMBS
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DOI：
10.1017/s0031182000043201
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发表时间：
1976-01-01
期刊：
影响因子：
2.4
通讯作者：
LEE, DL
中科院分区：
文献类型：
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作者：
MARTIN, J;LEE, DL
给60，000只感染N.从第20天开始，battus逐渐排出线虫成虫。大约在这个时候，成虫的肠道中出现了大的六角形晶体，并导致直肠-直肠或泄殖腔连接处堵塞。给羔羊1000-2000感染性幼虫没有摆脱感染;成年线虫从羔羊感染长达74天不包含这些晶体。化学、组织化学和X-射线微区分析表明，晶体的成分是脂蛋白。晶体出现在线虫的管腔内，似乎与羔羊对该线虫的免疫力的发展有关。
Lambs given 60,000 infective larvae of N. battus progressively threw off adult nematodes from day 20 onwards. Large, hexagonal crystals appeared in the intestine of the adult nematode at about this time and caused blockage of the intestinal-rectal or -cloacal junction. Lambs given 1000-2000 infective larvae did not throw off the infection; adult nematodes from lambs infected for up to 74 days did not contain these crystals. Chemical, histochemical and X-ray microanalysis tests on the crystals indicated that they are lipoprotein in composition. The crystals arise within the lumen of the nematode and appear to be associated with the development of immunity to this nematode in lambs.