Human soleus muscle architecture at different ankle joint angles from magnetic resonance diffusion tensor imaging
Human soleus muscle architecture at different ankle joint angles from magnetic resonance diffusion tensor imaging
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DOI：
10.1152/japplphysiol.00923.2010
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发表时间：
2011-03-01
影响因子：
3.3
通讯作者：
Edgerton, Reggie V.
中科院分区：
文献类型：
--
作者：
Sinha, Usha;Sinha, Shantanu;Edgerton, Reggie V.
肌纤维的取向影响生理横截面积，纤维缩短和腱膜剪切之间的关系，以及肌肉产生的总力。这样的结构参数是具有挑战性的，特别是在体内确定在多室结构，如人类比目鱼肌与复杂的肌纤维排列。本研究的目的是利用基于MRI的扩散张量成像（DTI）方法，在中性和跖屈踝关节位置的静息状态下，绘制人体比目鱼肌的纤维结构。六名受试者在3特斯拉下成像，脚在两个脚踝位置休息。本征值，分数各向异性（FA），并在不同的比目鱼肌亚室的纤维的特征向量取向进行了评价后，去噪的扩散张量。DTI的纤维结构与早期基于尸体3D纤维模型的研究相似。三个特征值的扩散张量增加了类似的14%，增加关节跖屈角在所有的比目鱼肌亚室，而FA显示出减少的趋势，在后方和边缘比目鱼肌和增加前比目鱼肌。两个足部位置之间的导联特征向量的角度变化是显著的：后比目鱼肌的角度变化类似于41度，前比目鱼肌的角度变化类似于48度。从子室跟踪的纤维支持在特征向量方向中看到的这些变化。DTI衍生的，特定于受试者的肌肉形态学数据可能被用于模拟更完整的肌肉性能和疾病变化的描述。
The orientation of muscle fibers influences the physiological cross-sectional area, the relationship between fiber shortening and aponeurosis shear, and the total force produced by the muscle. Such architectural parameters are challenging to determine particularly in vivo in multicompartment structures such as the human soleus with a complex arrangement of muscle fibers. The objective of this study was to map the fiber architecture of the human soleus in vivo at rest in both neutral and plantarflexed ankle positions using an MRI-based method of diffusion tensor imaging (DTI). Six subjects were imaged at 3 Tesla with the foot at rest in the two ankle positions. Eigenvalues, fractional anisotropy (FA), and eigenvector orientations of fibers in the different soleus subcompartments were evaluated after denoising of the diffusion tensor. The fiber architecture from DTI was similar to earlier studies based on a 3D fiber model from cadavers. The three eigenvalues of the diffusion tensor increased by similar to 14% on increasing the joint plantarflexion angle in all of the soleus subcompartments, whereas FA showed a trend to decrease in the posterior and marginal soleus and to increase in the anterior soleus. The angle change in the lead eigenvector between the two foot positions was significant: similar to 41 degrees for the posterior soleus and similar to 48 degrees for the anterior soleus. Fibers tracked from the subcompartments support these changes seen in the eigenvector orientations. DTI-derived, subject-specific, muscle morphological data could potentially be used to model a more complete description of muscle performance and changes from disease.