PROTEIN-A FROM STAPHYLOCOCCUS-AUREUS - BIOLOGICAL SIGNIFICANCE OF ITS REACTION WITH IGG
PROTEIN-A FROM STAPHYLOCOCCUS-AUREUS - BIOLOGICAL SIGNIFICANCE OF ITS REACTION WITH IGG
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DOI：
10.1111/j.1749-6632.1974.tb41496.x
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发表时间：
1974-01-01
影响因子：
5.2
通讯作者：
NORDSTRO.K
中科院分区：
文献类型：
--
作者：
FORSGREN, A;NORDSTRO.K
Protein A from Staphylococcus aureus was brought to common attention in 1958 by Jensen, l? 2 who found that most S. aureus strains contained an extractable product which precipitated with normal human serum and with normal human y-globulin. At that time, protein A was called antigen A and was considered to be a carbohydrate and a cell wall constituent; it was not liberated into the culture medium. At the same time, Beiser and colleagues3 independently showed that culture filtrates and bacterial extracts of S. aureus precipitated human immunoglobulins (IgG). In a more extensive study in 1962, Lofkvist and Sjoquist*-c, found that Jensen’s antigen A was a protein. Similar results were also obtained by Grov and colleagues. i
