Comparison of clinical characteristics of influenza and respiratory syncytial virus infection in hospitalised children and adolescents
Comparison of clinical characteristics of influenza and respiratory syncytial virus infection in hospitalised children and adolescents
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DOI：
10.1007/s00431-004-1445-6
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发表时间：
2004-07-01
影响因子：
3.6
通讯作者：
Heininger, U
中科院分区：
文献类型：
--
作者：
Meury, S;Zeller, S;Heininger, U
虽然儿科人群中呼吸道合胞病毒（RSV）感染导致的显著发病率已得到公认，但对欧洲主要健康儿童中流感的负担知之甚少。在我们的机构，瑞士的一所大学儿童医院，鼓励医务人员从因呼吸道症状住院的患者中采集鼻咽标本，进行甲型和B型流感、RSV和其他几种病原体的多重聚合酶链反应检测。我们利用这一策略，进行了一项回顾性研究，比较流感病毒感染的具体特点与RSV在连续两个冬季。总体而言，126例患者为RSV阳性，60例患者为流感阳性（A型：45例; B型：15例）。RSV、甲型流感和B流感感染儿童的中位年龄分别为4个月、2岁4个月和6岁2个月（P
While significant morbidity due to respiratory syncytial virus (RSV) infection in the paediatric population has been well acknowledged, little is known about the burden of influenza in primarily healthy children in Europe. In our institution, a University Children's Hospital in Switzerland, medical staff were encouraged to take nasopharyngeal specimens for multiplex polymerase chain reaction assays for influenza A and B, RSV and several other pathogens from patients hospitalised with respiratory symptoms. We took advantage of this strategy and performed a retrospective study to compare specific characteristics of influenza virus infections with those of RSV during two consecutive winter seasons. Overall, 126 patients were positive for RSV and 60 patients were positive for influenza (type A: 45; type B: 15). The median age of children with RSV, influenza A, and influenza B infection was 4 months; 2 years and 4 months; and 6 years and 2 months, respectively (P