Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds.
Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds.
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DOI：
10.1039/c3cc41558a
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发表时间：
2013-04
影响因子：
4.9
通讯作者：
Qicai Xue;Jin Xie;Huamin Li;Yixiang Cheng;Chengjian Zhu
中科院分区：
文献类型：
--
作者：
Qicai Xue;Jin Xie;Huamin Li;Yixiang Cheng;Chengjian Zhu
发展了一种在无金属条件下通过sp（3）C-H活化直接形成C-N键的新合成方法。伯苄基和仲苄基C-H底物都能与各种胺顺利反应，只得到单胺化产物，产率良好。
A new synthetic approach toward direct C-N bond formation through sp(3) C-H activation has been developed under metal-free conditions. Both primary and secondary benzylic C-H substrates could react smoothly with various amines to give only mono-amination products with good to excellent yields.