Localised nodular myositis: a clinical and pathological variant of polymyositis.
Localised nodular myositis: a clinical and pathological variant of polymyositis.
复制标题
局限性结节性肌炎：多发性肌炎的临床和病理变异。
DOI：
10.1093/oxfordjournals.qjmed.a067523
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
J. Walton
中科院分区：
文献类型：
--
作者：
W. Cumming;R. Weiser;R. Teoh;P. Hudgson;J. Walton
描述了三例年轻和中年成年男性的疼痛性、炎症性、结节性肌病病例。在其中两例中，结节性过程逐渐演变成弥漫性近端肌病，伴有吞咽困难，并表现为所谓的“面肩肱综合征”。所有三例病例的肌电图（EMG）均为“肌病”类型，并且在两例病例中观察到与炎症性肌肉疾病一致的异常。肌肉活检显示出一种一致的模式，即强烈的、主要是间质的、多形性的肌肉浸润，伴有分散的肌纤维破坏和再生灶，类似于肌肉梗塞。有人认为，这种综合征虽然从临床和病理学角度都很容易识别，但其本身并不是一个疾病学实体，而是多发性肌炎的一种不寻常表现。
Three cases of a painful, inflammatory, nodular myopathy in young and middle-aged adult males are described. In two of the cases the nodular process gradually evolved into a diffuse proximal myopathy accompanied by dysphagia, and manifesting the so-called "facioscapulohumeral syndrome". The electromyogram (EMG) in all three cases was "myopathic" in type and in two cases abnormalities consistent with an inflammatory muscle disorder were seen. Muscle biopsy revealed a consistent pattern of intense, predominantly interstitial, pleomorphic infiltration of muscle with scattered foci of muscle fibre destruction and regeneration, which resembled muscle infarcts. It is suggested that this syndrome, whilst readily recognizable from both the clinical and pathological standpoints, is not a nosological entity in its own right but rather an unusual presentation of polymyositis.