Risk factors for highly pathogenic H7N1 avian influenza virus infection in poultry during the 1999-2000 epidemic in Italy
Risk factors for highly pathogenic H7N1 avian influenza virus infection in poultry during the 1999-2000 epidemic in Italy
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DOI：
10.1016/j.tvjl.2008.02.013
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发表时间：
2009-08-01
影响因子：
2.2
通讯作者：
Marangon, Stefano
中科院分区：
文献类型：
--
作者：
Busani, Luca;Valsecchi, Maria Grazia;Marangon, Stefano
1999-2000年，意大利家禽生产因H7 N1亚型高致病性禽流感（HPAI）病毒流行而中断。本研究的目的是确定位于暴发次数最多的地区（韦内托和隆巴迪亚）的家禽养殖场的感染风险因素，以及作为根除感染补充措施的先发制人扑杀的影响。使用包括空间因素（如G指数）的考克斯回归模型。结果证实了感染风险与家禽品种、生产类型和养殖场规模的关系。先发制人的剔除的有效性得到了证实。位于受感染农场附近的家禽农场和海拔低于150米的家禽农场的感染风险增加。控制和根除禽流感病毒感染的措施需要考虑受影响地区家禽养殖场的易感性、生产类型和密度的物种差异。(c)2008爱思唯尔有限公司版权所有。
In 1999-2000, Italian poultry production was disrupted by an H7N1 virus subtype epidemic of highly pathogenic avian influenza (HPAI). The objectives of the present study were to identify risk factors for infection on poultry farms located in regions that had the highest number of outbreaks (Veneto and Lombardia) and the impact of pre-emptive culling as a complementary measure for eradicating infection. A Cox regression model that included spatial factors, such as the G index, was used. The results confirmed the relationship between risk of infection and poultry species, production type and size of farms. The effectiveness of pre-emptive culling was confirmed. An increased risk of infection was observed for poultry farms located near an infected farm and those at altitudes less than 150 in above sea level. The measures for the control and eradication of AI virus infection need to consider species differences in susceptibility, the types of production and the density of poultry farms in the affected areas. (c) 2008 Elsevier Ltd. All rights reserved.