Normalizing calcium intake: Projected population effects for body weight

Normalizing calcium intake: Projected population effects for body weight
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DOI:
10.1093/jn/133.1.268s
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发表时间:
2003-01-01
影响因子:
4.2
通讯作者:
Heaney, RP
Heaney, RP
中科院分区:
医学2区
文献类型:
--
作者:
Heaney, RP

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对564名妇女的钙摄入量和体重之间的负相关关系进行了评价,以确定其平均值的离散度,并根据相关变量的正态分布参数计算高于任何给定体重或体重增加率的分数。在钙摄入量的第25百分位数,15%的年轻女性超重,而在钙摄入量在目前推荐值范围内时,这一比例下降到只有4%。同样,在钙摄入量相同的情况下,该队列的肥胖患病率从1.4%下降到0.2%。在中年时,摄入量第25百分位的女性体重平均以0.42 kg/y的速度增加。在目前推荐的钙摄入量下,这一增量降至-0.011 kg/y。虽然钙摄入量只能解释体重或体重增加的一小部分变异性,但通过增加钙摄入量使分布的平均值向下移动,估计可使超重和肥胖的患病率降低60- 80%。
Published data describing the inverse relationship between calcium intake and body weight in 564 women were evaluated for their dispersion around their means, and the fraction above any given weight or rate of weight gain was calculated from the parameters of the normal distribution for the variable concerned. At the 25th percentile of calcium intakes, 15% of young women were overweight, and that fraction fell to only 4% at calcium intakes in the range of currently recommended values. Similarly, obesity prevalence in this cohort fell from 1.4 to 0.2% across the same difference in calcium intakes. At midlife, women at the 25th percentile of intakes gained weight, on average, at a rate of 0.42 kg/y. This gain dropped to -0.011 kg/y at currently recommended calcium intakes. Although calcium intake explains only a small fraction of the variability in weight or weight gain, shifting the mean of the distributions downward by increasing calcium intake can be estimated to reduce the prevalence of overweight and obesity by perhaps as much as 60-80%.