Haemophagocytic lymphohistiocytosis in a patient with severe burns

Haemophagocytic lymphohistiocytosis in a patient with severe burns
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严重烧伤患者噬血细胞性淋巴组织细胞增多症

DOI:
10.1111/anae.12062
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发表时间:
2013
期刊:
影响因子:
10.7
通讯作者:
S. Gurney
S. Gurney
中科院分区:
医学1区
文献类型:
--
作者:
J. R. Porter;J. Handy;H. Yarranton;S. Gurney

文献摘要

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Recently, increasing attention has been drawn to haemophagocytic lymphohistiocytosis as a potentially under‐diagnosed condition in critically ill patients with severe sepsis. It is thought to be caused by a highly stimulated, but ineffective, immune system. We report the case of a patient suffering from major burns who, despite extensive investigations showing the absence of concurrent sepsis or infection, developed haemophagocytic lymphohistiocytosis refractory to treatment. We believe that this is the first report suggestive of haemophagocytic lymphohistiocytosis triggered by a burns injury.