Cohort Profile: The Nijmegen Biomedical Study (NBS)
Cohort Profile: The Nijmegen Biomedical Study (NBS)
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DOI：
10.1093/ije/dyw268
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发表时间：
2017-08-01
影响因子：
7.7
通讯作者：
Kiemeney, Lambertus A. L. M.
中科院分区：
文献类型：
--
作者：
Galesloot, Tessel E.;Vermeulen, Sita H.;Kiemeney, Lambertus A. L. M.
奈梅亨生物医学研究（NBS）是一项基于人群的研究，于2000年在荷兰东部的奈梅亨市（15万居民）启动（由LK和AV）。国家统计局最初建立的目的是获得一个通用的参考人群，用于研究与感兴趣的特征或疾病有关的遗传变异、生活方式和环境暴露。然而，NBS也被证明对研究人口特征有用。国家统计局是由奈梅亨的Radboud大学医学中心（Radboudumc）的卫生证据部、实验室医学部和内科医学部与奈梅亨市政府和奈梅亨社区卫生服务机构合作建立的。后来，Radboudumc人类遗传学系加入了国家统计局的项目小组。从Radboud大学医学中心机构审查委员会获得了进行NBS的批准。所有参与者都提供了书面知情同意书。
The Nijmegen Biomedical Study (NBS) is a population-based study that was initiated (by LK and AV) in 2000 in the municipality of Nijmegen (150 000 inhabitants) in the eastern part of The Netherlands. The NBS was originally established to obtain a universal reference population to be used for studies of genetic variation, lifestyle and environmental exposures in relation to traits or diseases of interest. However, NBS has also proven useful for studying population traits. The NBS was set up by the Department for Health Evidence, the Department of Laboratory Medicine and the Department of Internal Medicine of the Radboud university medical center (Radboudumc) in Nijmegen in collaboration with the municipality of Nijmegen and the community health service of Nijmegen. At a later stage, the Department of Human Genetics of the Radboudumc joined the NBS project team. Approval to conduct the NBS was obtained from the Radboud university medical center Institutional Review Board. All participants gave written informed consent.