Contact Reactivity to Carcinogenic Polycyclic Hydrocarbons
Contact Reactivity to Carcinogenic Polycyclic Hydrocarbons
复制标题
与致癌多环烃的接触反应
DOI：
10.1038/1981215a0
复制
发表时间：
1963
期刊：
影响因子：
64.8
通讯作者：
Elizabeth A. Carswell
中科院分区：
文献类型：
--
作者：
L. J. Old;L. J. Old;B. Benacerraf;B. Benacerraf;Elizabeth A. Carswell;Elizabeth A. Carswell
ALTHOUGH the precise steps in chemical carcinogenesis are completely unknown, a stable interaction with some cellular component may well be an essential primary event in the process leading to malignancy. The binding of aminoazo dyes and polycyclic hydrocarbons to tissue proteins has been extensively investigated by the Millers1 and by Heidelberger et al.2. With chemical compounds of this type, there appears to be a correspondence between the degree of protein binding and the ability of an agent to function as a carcinogen.
