Inhibitory effects of urinary macromolecules on the crystallization of calcium oxalate.
Inhibitory effects of urinary macromolecules on the crystallization of calcium oxalate.
复制标题
尿大分子对草酸钙结晶的抑制作用。
DOI：
--
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
Roman Mj
中科院分区：
文献类型：
--
作者：
Gillette Wb;Karesh Jw;L. Garsin;Roman Mj
人类尿液大分子对草酸钙结晶的保护（抑制）作用被发现，当这些尿液大分子被添加到水或盐溶液中，这与人类尿液中最丰富的小分子量物种的浓度相似。尿液大分子对草酸钙结晶的影响有：(1)抑制成核（增加亚稳极限），(2)抑制结晶速率，(3)降低过饱和水平，(4)降低晶体与容器表面的粘附。
Protective (inhibitory) effects of human urinary macromolecules on the crystallization of calcium oxalate were found when these urinary macromolecules were added to water or to salt solutions, which mimic human urine with respect to the concentrations of the most abundant small molecular weight species. The aspects of calcium oxalate crystallization affected by urinary macromolecules were: (i) an inhibition of nucleation (increased metastable limit), (ii) an inhibition of the crystallization rate, (iii) a decrease in the supersaturation level, and (iv) a decrease in adhesion of crystals to container surfaces.