Fiber-optrode SERS probes using plasmonic silver-coated gold nanostars
Fiber-optrode SERS probes using plasmonic silver-coated gold nanostars
复制标题
使用等离激元镀银金纳米星的光纤电极 SERS 探针
DOI：
10.1016/j.snb.2019.01.167
复制
发表时间：
2019-05-15
影响因子：
8.4
通讯作者：
Vo-Dinh, Tuan
中科院分区：
文献类型：
--
作者：
Ran, Yang;Strobbia, Pietro;Vo-Dinh, Tuan
基于表面增强拉曼散射 (SERS) 的分子传感已成为从环境监测、生物医学诊断到安全应用等众多领域的强大工具。作为多功能 SERS 探针，光纤电极（即集成在光纤上的 SERS 基板）可以同时引导激发激光并收集拉曼信号，从而实现远程和原位传感功能。这一特性使光纤极非常适合危险环境或现场应用，在这些应用中样品操作必须最少。在本文中，我们首先报道了使用银包金纳米星（Au@Ag NS）作为高度增强的SERS活性基底的光纤电极的开发。这些光极利用 Au@Ag NS 优异的光子特性来实现超灵敏的传感特性。通过 Au@Ag NS 纳米颗粒的固定和光极配置的优化，对所提出的 SERS 传感器的分析品质因数进行了详细研究。本文开发的光极在痕量化学品的现场和远程测试以及食品添加剂和生物靶标的直接检测等应用中具有广阔的前景。
Surface-enhanced Raman scattering (SERS)-based molecular sensing has emerged as a powerful tool in a wide variety of fields ranging from environmental monitoring, biomedical diagnostics to security applications. As versatile SERS probes, fiber-optrodes (i.e., a SERS substrate integrated on optical fibers) can simultaneously guide excitation laser and collect the Raman signal, enabling remote and in situ sensing capabilities. This characteristic feature makes fiber-optrodes ideal for hazardous environments or for field-ready applications, where sample manipulation has to be minimal. In this paper, we firstly report the development of a fiber-optrode using silver-coated gold nanostars (Au@Ag NS) as highly enhancing SERS active substrate. These optrodes take advantage of the excellent photonic properties of Au@Ag NS to achieve ultra-sensitive sensing properties. Through the immobilization of the Au@Ag NS nanoparticles and the optimization of the optrode-configuration, the proposed SERS sensor's analytical figures of merit are investigated in detail. The optrode developed herein has a promising prospect for in-field and remote test for trace chemicals and for applications such as direct detection of food additives and biotargets.