CIGARETTE-SMOKING - A RISK FACTOR FOR HEMORRHAGIC AND NONHEMORRHAGIC STROKE
CIGARETTE-SMOKING - A RISK FACTOR FOR HEMORRHAGIC AND NONHEMORRHAGIC STROKE
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DOI：
10.1001/archinte.149.9.2053
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发表时间：
1989-09-01
影响因子：
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通讯作者：
BEEVERS, DG
中科院分区：
文献类型：
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作者：
GILL, JS;SHIPLEY, MJ;BEEVERS, DG
采用病例对照研究方法，对621例脑卒中患者和573例对照者的吸烟习惯进行了研究。与对照组相比，中风组中吸烟者过多。调整蛛网膜下腔出血、脑内出血和脑梗死的可能混杂变量后，吸烟者与不吸烟者相比的相对危险度男性分别为4.5、1.8和3.2，女性分别为2.5、1.3和2.3。对于合并的所有中风亚型，增加的相对危险度与每日吸烟量有关，重度吸烟者的相对危险度高于轻度吸烟者。吸烟者的相对风险估计增加1.5每天吸烟每10支香烟在男性和女性。我们的结论是，吸烟可能是出血性和非出血性中风的一个重要的可预防因素。
Cigarette smoking habit was studied in 621 patients with stroke and in 573 control subjects using case control methods. There was an excess of smokers among the stroke group when compared with control subjects. Relative risks of cigarette smokers compared with nonsmokers, after adjustment for the possible confounding variables for subarachnoid hemorrhage, intracerebral hemorrhage, and cerebral infarction, were 4.5, 1.8, and 3.2 for men and 2.5, 1.3, and 2.3 for women, respectively. For all subtypes of stroke combined, the increased relative risk was related to the daily intake of cigarettes, the heaviest smokers having a higher relative risk than that for light smokers. The estimated increase in relative risk among smokers was 1.5 for each 10 cigarettes smoked daily in both men and women. We conclude that cigarette smoke may be an important preventable factor for both hemorrhagic and nonhemorrhagic stroke.