Sleep apnea risk and clinical correlates in patients with bipolar disorder
Sleep apnea risk and clinical correlates in patients with bipolar disorder
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DOI：
10.1111/j.1399-5618.2012.01044.x
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发表时间：
2012-09-01
影响因子：
5.4
通讯作者：
Kupfer, David J.
中科院分区：
文献类型：
--
作者：
Soreca, Isabella;Levenson, Jessica;Kupfer, David J.
Soreca I，Levenson J，Lotz M，Frank E，Kupfer DJ.双相情感障碍患者的睡眠呼吸暂停风险和临床相关性双相情感障碍2012：14：672676。(c)2012作者期刊汇编（c）2012年约翰威利父子A/S。目的：尽管在双相情感障碍患者中阻塞性睡眠呼吸暂停（OSA）的危险因素的患病率很高，但在这一人群中睡眠呼吸障碍的存在尚未得到系统的评估。在这项研究中，我们试图确定一个缓解的个人诊断为双相I型障碍的人群中OSA的风险水平。研究方法：共有72名被诊断为双相I型障碍的患者完成了柏林问卷调查，这是一种自我评估工具，用于确定OSA的风险。结果：超过一半的研究人群（54.1%）被发现属于OSA的高风险类别。OSA高风险参与者在抑郁和躁狂两项指标上的得分都显着更高，即使睡眠项目没有计入总分。结论：睡眠呼吸暂停可能在双相I型障碍患者中普遍存在。考虑到阻塞性睡眠呼吸暂停和抑郁症之间的大量重叠的症状和潜在的有害影响的睡眠中断的患者的情绪障碍，一个系统的筛选，以评估患病率和相关特征的双相情感障碍患者的阻塞性睡眠呼吸暂停是必要的。
Soreca I, Levenson J, Lotz M, Frank E, Kupfer DJ. Sleep apnea risk and clinical correlates in patients with bipolar disorder. Bipolar Disord 2012: 14: 672676. (c) 2012 The Authors. Journal compilation (c) 2012 John Wiley & Sons A/S. Objective: Despite the high prevalence of risk factors for obstructive sleep apnea (OSA) among individuals with bipolar disorder, the presence of sleep-disordered breathing has not been systematically assessed in this population. In this study, we sought to determine the level of risk for OSA in a population of remitted individuals with a diagnosis of bipolar I disorder. Methods: A total of 72 individuals with a diagnosis of bipolar I disorder, all of whom were overweight by the World Health Organization criteria, completed the Berlin Questionnaire, a self-assessment tool to establish risk for OSA. Results: Over half of this study population (54.1%) was found to be in the high-risk category for OSA. Participants at high risk for OSA scored significantly higher on measures of both depression and mania, even when sleep items were not counted in the total scores. Conclusions: Sleep apnea may be prevalent in patients with bipolar I disorder. Considering the substantial overlap of symptoms between OSA and depression and the potentially harmful effects of sleep disruption in patients with mood disorders, a systematic screening to assess prevalence and associated features of OSA in patients with bipolar disorder is warranted.