T1 and T2 measurements of the fine structures of the in vivo and enucleated human eye
T1 and T2 measurements of the fine structures of the in vivo and enucleated human eye
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DOI：
10.1002/jmri.21017
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发表时间：
2007-09-01
影响因子：
4.4
通讯作者：
Freddo, Thomas F.
中科院分区：
文献类型：
--
作者：
Patz, Samuel;Bert, Robert J.;Freddo, Thomas F.
目的：测量活体眼精细结构的T-1和T-2。材料和方法：无意识扫视使获得无伪影图像变得困难。使用最近报道的方法（Bert等人，Acad Radiol 2006; 12：368-378），获得了接近无伪影的自旋回波图像。在1.5T下研究了一只离体眼球和八名人类受试者。获取自旋回波可变TRITE数据用于T-1/T-2测定。平均放松时间通过两种方式计算。首先，计算不同受试者的算术平均值。结果：体内T-1/T-2（msec）分别为：算术平均值T-1、T-2，归一化数据T1、T2。前房：6233 +/- 979，468 +/- 149，5053 +/- 1052，450 1 +/- 49。睫状体：1916 +/- 184，80 +/- 7，2038 +/- 114，76 +/- 3。脉络膜视网膜：1717 +/- 500，72 +/- 25，1511 1 +/- 230，78 +/- 3。眼外肌：1581 +/- 646，41 +/- 7，1470 +/- 231，41 +/- 1。虹膜：3334 +/- 989，163 +/- 63，3376 +/- 338，153 +/- 10。透镜皮质：1712 +/- 466、93 +/- 36、1413 +/- 177、100 +/- 5。透镜核：1133 +/- 40，26 +/- 3，1138 +/- 47，25 +/- 0.4。视神经：1906 +/- 301，6816，1805 +/- 244，71 +/- 2。后房：7915 +/- 4897，241 +/- 14，3323 +/- 2154，251 +/- 38。活力幽默：5768 ± 1190，756 ± 804，4855 ± 1846，390 ± 8。结论：在活体条件下，测量了人眼许多细微结构的T-1和T-2。
Purpose: To measure T-1 and T-2 of the fine structures of the in vivo eye.Materials and Methods: Involuntary saccades make it difficult to obtain artifact-free images. Using a method recently reported (Bert et al, Acad Radiol 2006; 12:368-378), near artifact-free spin-echo images were obtained. Both an isolated enucleated eye and eight human subjects were studied at 1.5T. Spin-echo variable TRITE data was acquired for T-1/T-2 determination. Average relaxation times were calculated two ways. First, an arithmetic average over different subjects was computed. Second, all data was normalized using the fitted amplitudes of each data set and pooled to obtain a single least squares fit.Results: In vivo T-1/T-2 (msec) are: arithmetic average T-1, T-2, normalized data T1, T2. Anterior chamber: 6233 +/- 979, 468 +/- 149, 5053 +/- 1052, 450 1 +/- 49. Ciliary body: 1916 +/- 184, 80 +/- 7, 2038 +/- 114, 76 +/- 3. Chorioretina: 1717 +/- 500, 72 +/- 25, 1511 1 +/- 230, 78 +/- 3. Extraocular muscle: 1581 +/- 646, 41 +/- 7, 1470 +/- 231, 41 +/- 1. Iris: 3334 +/- 989, 163 +/- 63, 3376 +/- 338, 153 +/- 10. Lens cortex: 1712 +/- 466, 93 +/- 36, 1413 +/- 177, 100 +/- 5. Lens nucleus: 1133 +/- 40, 26 +/- 3, 1138 +/- 47, 25 +/- 0.4. Optic nerve: 1906 +/- 301, 6816, 1805 +/- 244, 71 +/- 2. Posterior chamber: 7915 +/- 4897, 241 +/- 14, 3323 +/- 2154, 251 +/- 38. Vitreous humor: 5768 +/- 1190, 756 +/- 804, 4855 +/- 1846, 390 +/- 8.Conclusion: In vivo T-1 and T-2 for many of the fine structures of the human eye have been measured.