Evaluation of the right and left ventricles: An integrated approach measuring the area, length, and width of the chambers in normal fetuses
Evaluation of the right and left ventricles: An integrated approach measuring the area, length, and width of the chambers in normal fetuses
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DOI：
10.1002/pd.5166
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发表时间：
2017-12-01
影响因子：
3
通讯作者：
Sklansky, Mark
中科院分区：
文献类型：
--
作者：
DeVore, Greggory R.;Klas, Berthold;Sklansky, Mark
本研究的目的是用斑点追踪软件同时测量舒张末期心室面积（A）、基底横宽（BW）、中腔横宽（MW）、方法对200例孕20 ~ 40周的正常胎儿和9例孕3 ~ 4周的正常胎儿心脏进行四腔心切面的测量，并与正常胎儿和病理胎儿进行比较。心脏畸形的三个月胎儿A，BW，MW，和BAL的平均值和标准差计算从控制胎儿和Z分数计算从9个胎儿心脏malformation.ResultsThe A，BAL，BW，和MW与7个躯体和年龄无关的变量（R-2= 0.63 - 0.85）。最高的R-2值出现在头围、估计的胎儿体重和超声平均胎龄（0.82 - 0.85）。Z-评分值和百分位数从9个胎儿心脏畸形表明，A，BW，MW，和BAL低于或高于第5和第95百分位数预期为相应的ventricular pathology.ConclusionsThis研究报告了一个综合的方法来评估舒张末期大小的右心室和左心室腔室，并表现出临床效用胎儿心脏畸形。
IntroductionThe purpose of this study was to simultaneously measure with speckle tracking software the end-diastolic ventricular area (A), basal transverse width (BW), mid-chamber transverse width (MW), and basal-apical length (BAL) in normal fetuses and those with pathology.MethodsThe 4-chamber view of the fetal heart was obtained in 200 control fetuses between 20 and 40weeks of gestation and in 9 third-trimester fetuses with heart malformations. The mean and standard deviation for the A, BW, MW, and BAL were computed from the control fetuses and Z scores computed from the 9 fetuses with cardiac malformations.ResultsThe A, BAL, BW, and MW were correlated with 7 somatic and age-independent variables (R-2=.63-.85). The highest R-2 values occurred for the head circumference, estimated fetal weight, and ultrasound mean gestational age (.82-.85). Z-score values and centiles from the 9 fetuses with cardiac malformations suggested that the A, BW, MW, and BAL were below or above the 5th and 95th centiles as expected for the corresponding ventricular pathology.ConclusionsThis study reports an integrated approach to evaluate the end-diastolic size of the right and left ventricular chambers and demonstrated clinical utility in fetuses with cardiac malformations.