SHARK CARTILAGE CONTAINS INHIBITORS OF TUMOR ANGIOGENESIS
SHARK CARTILAGE CONTAINS INHIBITORS OF TUMOR ANGIOGENESIS
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DOI：
10.1126/science.6193581
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发表时间：
1983-01-01
期刊：
影响因子：
56.9
通讯作者：
LANGER, R
中科院分区：
文献类型：
--
作者：
LEE, A;LANGER, R
鲨鱼软骨中含有一种物质，可以强烈抑制新血管向实体瘤生长，从而限制肿瘤生长。鲨鱼软骨中这种因子的丰度与哺乳动物来源的软骨相反，可能使鲨鱼成为抑制剂的理想来源，并可能有助于解释这些动物中肿瘤的罕见性。
Shark cartilage contains a substance that strongly inhibits the growth of new blood vessels toward solid tumors, thereby restricting tumor growth. The abundance of this factor in shark cartilage, in contrast to cartilage from mammalian sources, may make sharks an ideal source of the inhibitor and may help to explain the rarity of neoplasms in these animals.