DIETARY PATTERNS AND COGNITIVE HEALTH IN OLDER ADULTS: FINDINGS FROM THE SYDNEY MEMORY AND AGEING STUDY
DIETARY PATTERNS AND COGNITIVE HEALTH IN OLDER ADULTS: FINDINGS FROM THE SYDNEY MEMORY AND AGEING STUDY
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DOI：
10.1007/s12603-020-1536-8
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发表时间：
2021-02-01
影响因子：
5.8
通讯作者：
Brodaty, Henry
中科院分区：
文献类型：
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作者：
Chen, X.;Liu, Z.;Brodaty, Henry
目的：系统评价报告饮食模式可能与老年人的认知健康有关。然而，研究结果不一致，相关研究缺乏大规模的研究。本研究旨在探讨澳大利亚老年人的饮食模式和认知功能之间的关系。设计：以人群为基础，对悉尼记忆和老龄化研究（一项特征鲜明的澳大利亚老龄化研究）的基线阶段进行横断面分析。悉尼记忆和衰老研究于2005年启动，旨在检查轻度认知障碍（MCI）的临床特征和患病率。参与者：在悉尼记忆和衰老研究中，随机抽取了选民名册上的8914名个人，从悉尼两个地区招募了70-90岁的英语背景的非痴呆社区居民（N = 819）。测量：癌症委员会维多利亚州理事会食物频率问卷用于评估饮食摄入量。生成了地中海饮食、阻止高血压饮食方法（DASH）饮食和饮食指南指数（DGI 2013）的评分。两种模式-一个谨慎的健康和西方的饮食模式-使用主成分分析（PCA）。神经心理学测试用于评估整体认知和六个认知领域。多变量线性模型评估饮食模式和认知领域scores.Results之间的关系：地中海饮食和DASH饮食都与视觉空间认知呈正相关（P=0.002和P=0.001）。豆类和坚果的摄入量越高，整体认知（beta=0.117; 95%CI：0.052，0.181; P < 0.001）以及语言和视觉空间认知领域的表现越好。谨慎的健康饮食与更好的全球认知有关（β =0.307; 95% CI：0.053，0.562; P=0.019），而西方饮食与整体功能较差相关（β =-0.242; 95% CI：-0.451，-0.034; P=0.023）和执行功能男性（β =-0.325; 95%CI：-0.552，-0.099; P=0.005）。结论：在这项分析中，更高的地中海饮食，DASH饮食，谨慎的健康饮食以及更多的豆类和坚果消费与老年人更好的认知相关。
Objectives: Systematic reviews report dietary patterns may be associated with cognitive health in older adults. However, inconsistent findings have been reported and relevant research lacks large scale studies. This study aims to examine the associations of dietary patterns and cognitive function among older adults in an Australian ageing cohort.Design: A population-based, cross-sectional analysis of the baseline phase of the Sydney Memory and Ageing Study, a well-characterised Australian ageing study.Setting: The Sydney Memory and Ageing Study was initiated in 2005 to examine the clinical characteristics and prevalence of mild cognitive impairment (MCI).Participants: Non-demented community-dwelling individuals from English- speaking background (N = 819) aged 70-90 recruited from two areas of Sydney, following a random approach to 8914 individuals on the electoral roll in the Sydney Memory and Ageing study.Measurements: The Cancer Council of Victoria Food Frequency Questionnaire was used to assess dietary intake. Scores for Mediterranean diet, Dietary Approaches to Stop Hypertension (DASH) diet and the Dietary Guidelines Index (DGI 2013) were generated. Two patterns - a Prudent healthy and a Western dietary pattern - were derived using principal components analysis (PCA). Neuropsychological tests were used to assess global cognition and six cognitive domains. Multivariate linear modelling assessed the relationship between dietary patterns and cognitive domain scores.Results: Mediterranean diet and DASH diet were both positively linked to visuospatial cognition (P=0.002 and P=0.001 respectively). Higher intake of legumes and nuts was related to better performance in global cognition (beta=0.117; 95% CI:0.052, 0.181; P < 0.001) and language and visuospatial cognitive domains. The Prudent healthy diet was associated with better global cognition (beta=0.307; 95% CI: 0.053, 0.562; P=0.019) in women and a Western diet was related to poorer global function (beta=-0.242; 95% CI: -0.451,-0.034; P=0.023) and executive function (beta=-0.325; 95% CI: -0.552,-0.099; P=0.005) in men.Conclusion: In this analysis, higher adherence to the Mediterranean diet, DASH diet, Prudent healthy diet and greater consumption of legumes and nuts were associated with better cognition among older adults.