Breast MR imaging in patients with axillary node metastases and unknown primary malignancy
Breast MR imaging in patients with axillary node metastases and unknown primary malignancy
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DOI：
10.1148/radiology.212.2.r99au40543
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发表时间：
1999-08-01
期刊：
影响因子：
19.7
通讯作者：
Solin, LJ
中科院分区：
文献类型：
--
作者：
Orel, SG;Weinstein, SP;Solin, LJ
目得：评估乳腺磁共振（MR）成像在恶性腋窝淋巴结病和未知的原发malignancy.MATERIALS和METHODS：1993年10月至1997年12月，38例恶性腋窝淋巴结病和阴性乳腺X线摄影和体检结果的妇女进行了对比剂增强MR成像的有用性。16例患者因腋尾癌（n = 7）、缺乏随访（n = 4）、第二原发恶性肿瘤（n = 3）或MR成像前化疗（n = 2）而被排除。研究人群包括其余22例患者。病理结果可在20例;后续MR成像结果可在2 patients.RESULTS：MR成像描绘了原发性乳腺癌19例（86%，确定在切除活检或乳房切除术17，解决在治疗过程中的后续MR图像）。MR成像显示4-30 mm（平均17 mm）的癌，与组织病理学大小密切相关。2例患者（9%）有假阴性结果：（a）1例为2 mm浸润性导管癌，（B）1例为17 mm和20 mm浸润性导管癌。在19例患者中，11例进行了乳房切除术，7例进行了乳房保护治疗，1例没有接受手术procedure.CONCLUSION：MR成像是非常敏感的检测乳腺癌和临床隐匿性乳腺癌患者恶性腋窝淋巴结肿大。在这些患者中，MR成像不仅提供了癌症检测的潜力，而且还提供了乳腺癌分期的潜力，这可能有助于制定治疗计划。
PURPOSE: To assess the usefulness of magnetic resonance (MR) imaging of the breast in patients with malignant axillary adenopathy and unknown primary malignancy.MATERIALS AND METHODS: Between October 1993 and December 1997, 38 women with malignant axillary adenopathy and negative mammographic and physical examination findings underwent contrast material-enhanced MR imaging. Sixteen patients were excluded due to axillary tail cancer (n = 7), lack of follow-up (n = 4), second primary malignancy (n = 3), or chemotherapy before MR imaging (n = 2). The study population comprised the remaining 22 patients. Histopathologic findings were available in 20 patients; follow-up MR imaging findings were available in two patients.RESULTS: MR imaging depicted a primary breast cancer in 19 patients (86%; identified at excisional biopsy or mastectomy in 17, resolved on follow-up MR images during treatment in two). MR imaging depicted 4-30-mm cancers (mean, 17 mm), which correlated closely with histopathologic size. Two patients (9%) had false-negative findings: (a) One had a 2-mm invasive ductal carcinoma, and (b) one had 17- and 20-mm invasive ductal carcinomas. Of the 19 patients, 11 underwent mastectomy, seven underwent breast-conservation therapy, and one did not undergo a surgical procedure.CONCLUSION: MR imaging is very sensitive for the detection of mammographically and clinically occult breast cancer in patients with malignant axillary adenopathy. In these patients, MR imaging offers potential not only for cancer detection but also for staging the cancer within the breast, which may be useful for treatment planning.