Eruption rates of impeded and unimpeded mandibular incisors of the adult laboratory mouse
Eruption rates of impeded and unimpeded mandibular incisors of the adult laboratory mouse
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DOI：
10.1016/0003-9969(65)90109-3
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发表时间：
1965-01-01
期刊：
影响因子：
3
通讯作者：
NESS, A. R.
中科院分区：
文献类型：
--
作者：
NESS, A. R.
11只成年实验室小鼠（Mus musculus）的下颌切牙萌出率每周测量3次，共5周，分为3个时期：L为5个间隔，萌出自然受阻; II为5个间隔，其中左切牙被人为缩短，萌出不受阻碍; HI为4个间隔，其中咬合恢复正常。抑制喷发的平均速率为156[mu]/天，S.D.53。在第二阶段，左切牙的不受阻碍的萌出平均为414[mu]/天，标准差72：这些速率令人惊讶，因为根据已知的大鼠、豚鼠、兔和海狸鼠，预期值> 1000[mu]/天。在第二阶段，右下颌切牙平均缩短0.43mm，水平角增大，萌出率显著增加，平均315亩/日，S.D. 48亩/天。在第III阶段，未出现皮疹率的抑制：最后两个结果将小鼠与家兔进行了对比。随机和系统误差的来源被证明不会影响显着的主要结果，也没有在第一阶段（r = +0.78）和第二阶段（r = +0.45）的门牙对萌出率之间的相关性。在第三期，切间骨尖显示出可解释为左尖骨质溶解的变化，约为58[mu];在此期间，门牙也明显分开，约为40[mu]。没有相关性之间的阻碍和畅通率的萌出门牙。|| 摘要编辑：作者
The eruption rates of the mandibular incisors of eleven adult laboratory mice (Mus musculus) were measured thrice a week for 5 weeks in three periods: L of five intervals, eruption being naturally impeded; II, of five intervals in which the left incisors, being shortened artificially, erupted unimpeded; HI of four intervals, in which occlusion returned to normal. Impeded eruption was at rates averaging 156[mu]/day, S.D.53. Unimpeded eruption of the left incisors in Period-II averaged 414[mu]/day, S.D.72: these rates were a surprise, for values > 1000[mu]/day were expected from what was known of rat, cavy, rabbit and coypu. During Period-II the right mandibular incisors shortened on average 0.43 mm, increased their level angles and greatly increased in rate of eruption to average 315 [mu]/day, S.D. 48 [mu]/day. Depression of rates of eruption did not follow in Period III: these last two results contrast mouse with rabbit. Sources of random and systematic error were shown not to affect significantly the main results, nor the correlations between the eruption rates of an incisor pair during Period-I (r = +0.78) and Period-II (r = +0.45). The interincisal bony tips showed changes interpretable as osteolysis of the left tip by about 58[mu] during Period-III; in which period the incisors also moved apart, apparently bodily, by about 40[mu]. No correlation was found between the impeded and the unimpeded rates of eruption of an incisor. || ABSTRACT AUTHORS: Author