IMMUNE COMPLEX-TRAPPING CELLS IN THE SPLEEN OF THE CHICKEN - ENZYME HISTOCHEMICAL AND ULTRASTRUCTURAL ASPECTS
IMMUNE COMPLEX-TRAPPING CELLS IN THE SPLEEN OF THE CHICKEN - ENZYME HISTOCHEMICAL AND ULTRASTRUCTURAL ASPECTS
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DOI：
10.1007/bf00222188
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发表时间：
1983-01-01
影响因子：
3.6
通讯作者：
VANROOIJEN, N
中科院分区：
文献类型：
--
作者：
EIKELENBOOM, P;KROESE, FGM;VANROOIJEN, N
应用免疫组织过氧化物酶技术和HRP-抗HRP复合物对鸡脾脏滤泡树突状细胞进行了光镜和超微结构观察。与哺乳动物中的发现相反，鸡脾脏中的滤泡树突状细胞显示出明显的酸性磷酸酶活性，并具有相当数量的初级溶酶体。静脉注射免疫复合物后，在Schweigger-Seidel鞘的外周部分发生短暂的免疫复合物捕获。在Schweigger-Seidel鞘和生发中心的免疫复合物捕获细胞显示出相同的酶组织化学模式，只有微小的差异，在超微结构的特点。静脉注射免疫复合物和碳颗粒后不久，这些化合物显示出相同的分布模式，然而，在接下来的日子里，这些分布模式变得分歧。
By means of immunohistoperoxidase techniques and the use of HRP-anti-HRP complexes, follicular dendritic cells in chicken spleen can be characterized both at the light-microscopical and ultrastructural level. In contrast to findings in mammals follicular dendritic cells in chicken spleen exhibit evident acid-phosphatase activity and possess considerable numbers of primary lysosomes. After intravenous injection of immune complexes a transient immune complex-trapping occurs in the peripheral parts of the Schweigger-Seidel sheath. The immune complextrapping cells in the Schweigger-Seidel sheath and germinal centre show an identical enzyme histochemical pattern and only minor differences in ultrastructural characteristics.Shortly after intravenous injection of immune complexes and carbon particles these compounds show an identical distribution pattern; however, in the following days these distribution patterns become divergent.