Risk of cervical intraepithelial neoplasia grade 2 or 3 after loop electrosurgical excision procedure associated with human papillomavirus type 16 variants.
Risk of cervical intraepithelial neoplasia grade 2 or 3 after loop electrosurgical excision procedure associated with human papillomavirus type 16 variants.
复制标题
与人乳头瘤病毒 16 型变种相关的环形电外科切除手术后发生 2 级或 3 级宫颈上皮内瘤变的风险。
DOI：
10.1086/513441
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Koutsky,LauraA
中科院分区：
文献类型：
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作者：
Xi,LongFu;Kiviat,NancyB;Wheeler,CosetteM;Kreimer,Aimee;Ho,Jesse;Koutsky,LauraA
Identification of factors associated with risk of relapse after treatment for high-grade cervical intraepithelial neoplasia (CIN) has important clinical implications. Study subjects were women participating in the Atypical Squamous Cells of Undetermined Significance and Low-Grade Squamous Intraepithelial Lesion Triage Study who were treated for CIN3 by loop electrosurgical excision procedure (LEEP) and who had a baseline infection with human papillomavirus type 16 (HPV16). These women were followed every 6 months for 2 years. Post-LEEP CIN2-3 was found in 20 (10.0%) of the 201 women. An adjusted relative risk of 3.1 (95% confidence interval, 1.1–8.9) was associated with HPV16 non-European, compared with European, variants, a finding that is consistent with the variant-related risk of prevalent/incident high-grade CIN.
