HIV Infection in Older Adults

HIV Infection in Older Adults
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DOI:
10.1016/j.cger.2007.02.004
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发表时间:
2007-08-01
影响因子:
3.3
通讯作者:
Wilkin, Aimee M.
Wilkin, Aimee M.
中科院分区:
医学3区
文献类型:
--
作者:
Luther, Vera P.;Wilkin, Aimee M.

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老年人感染艾滋病毒的发病率和流行率正在上升,妇女和少数群体的发病率和流行率不成比例地增加。与年轻人相比,感染艾滋病毒的老年患者往往在疾病过程中被诊断出来,并且可能会加速免疫功能的下降。虽然随着高效抗逆转录病毒治疗的开始,老年人的预后有所改善,但合并症的风险仍然较高。必须作出更多努力,诊断和预防这一老年群体的艾滋病毒感染,以减少艾滋病毒的传播,并降低与这一感染有关的发病率和死亡率。
The incidence and prevalence of HIV infection in older adults is rising, with disproportionate increases in women and minorities. Compared with younger adults, older patients who have HIV often are diagnosed later in the course of the disease and may have an accelerated decline in immune function. Although the prognosis for older adults has improved with the initiation of highly active antiretroviral therapy, there remains a higher risk for comorbid illness. Additional efforts to diagnose and prevent HIV infection in this older age group are necessary to decrease the transmission of HIV and to reduce the morbidity and mortality associated with this infection.