Effects of extra irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene
Effects of extra irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene
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额外辐照对 PMPC 接枝交联聚乙烯表面和本体性能的影响
DOI：
10.1002/jbm.a.35538
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Kazuhiko Ishihara
中科院分区：
文献类型：
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作者：
Shihori. Yamane;Masayuki Kyomoto;Toru Moro;Kenichi Watanabe;Masami Hashimoto;Yoshio Takatori;Sakae Tanaka;Kazuhiko Ishihara
在全髋关节置换术（THA）中使用超高分子量聚乙烯髋臼衬垫进行高能辐照灭菌是一个重要方面。在这项研究中，我们评估了在灭菌过程中额外辐照，如伽马射线或等离子体辐照，对聚（2 -甲基丙烯酰氧乙基磷酸胆碱[MPC]） （PMPC）表面和交联聚乙烯（CLPE）底物进行PMPC接枝CLPE髋臼衬垫的影响。与未处理的CLPE相比，PMPC接枝的表面具有高润湿性和低摩擦性能，而不受额外辐照的影响。在髋关节模拟器测试中，由于PMPC表面的高润湿性，PMPC -接枝CLPE衬垫在额外照射后仍能保持耐磨性。特别是，等离子体辐照处理的PMPC接枝CLPE衬垫的润湿性和耐磨性优于伽马射线辐照处理。然而，我们不能清楚地观察到两次额外辐照后PMPC表面化学性质和形貌的变化。由于CLPE基材性能的影响，其物理和机械性能也保持不变。相比之下，等离子体辐照处理的PMPC -接枝CLPE在加速老化后表现出比伽马射线辐照处理更好的抗氧化性。因此，我们得出结论，PMPC移植的CLPE与等离子体照射有希望作为THA的终身解决方案。©2015 Wiley期刊公司[J] .中国生物医学工程学报，2016,31(1):557 - 557。
Sterilization using high‐energy irradiation is an important aspect of implementing an ultra‐high molecular weight polyethylene acetabular liner in total hip arthroplasty (THA). In this study, we evaluate the effects of extra irradiations such as gamma‐ray or plasma irradiation during sterilization of the poly(2‐methacryloyloxyethyl phosphorylcholine [MPC]) (PMPC) surface and cross‐linked polyethylene (CLPE) substrate of a PMPC‐grafted CLPE acetabular liner. The PMPC‐grafted surface yielded high wettability and low friction properties regardless of the extra irradiations as compared with untreated CLPE. During a hip simulator test, wear resistance of the PMPC‐grafted CLPE liner was maintained after extra irradiation, which is due to the high wettability characteristics of the PMPC surface. In particular, the PMPC‐grafted CLPE liner treated with plasma irradiation showed greater wettability and wear resistance than that with gamma‐ray irradiation. However, we could not clearly observe the changes in chemical properties and morphology of the PMPC surface after both extra irradiations. The physical and mechanical properties attributed to CLPE substrate performance were also unchanged. In contrast, PMPC‐grafted CLPE treated with plasma irradiation showed improved oxidation resistance as compared to that treated with gamma‐ray irradiation after accelerated aging. Thus, we conclude that PMPC‐grafted CLPE with plasma irradiation has promise as a lifelong solution for bearing in THA. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 37–47, 2016.