The Accuracy of Cardiac Surface Conduction Velocity Measurements

The Accuracy of Cardiac Surface Conduction Velocity Measurements
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心脏表面传导速度测量的准确性

DOI:
10.1101/2024.01.26.24301849
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发表时间:
2024
期刊:
--
影响因子:
--
通讯作者:
Vigmond E
Vigmond E
中科院分区:
--
文献类型:
--
作者:
Vigmond E

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背景传导速度(CV)是衡量心肌组织健康状况的指标。它可以通过测量心内电极局部激活时间的差异来测量。有几个因素会给测量带来误差,其中忽略三维方面是一个主要的不利因素。目的本研究的目的是确定是否存在一个特定的区域可以准确地测量CV值。脑室还包括密集的疤痕或弥漫性纤维组织。结果更精细的空间采样与真实的CV更符合。以10厘米/S的误差极限为阈值,在距离起搏部位2厘米的区域内进行的测量被证明是准确的。误差突然增加,超过了这个距离。浦肯野系统和组织纤维取向在导致表面变异不能反映通过组织传播的变异中起着同样重要的作用。只有接近起搏部位的表面CV测量才能给出合理的估计,这些测量是在电极间距为≤1 mm的情况下进行的。
BackgroundConduction velocity (CV) is a measure of the health of myocardial tissue. It can be measured by taking differences in local activation times from intracardiac electrodes. Several factors introduce error into the measurement, among which ignoring the 3-dimensional aspect is a major detriment.ObjectiveThe purpose of this study was to determine if, nonetheless, there was a specific region where CV could be accurately measured.MethodsComputer simulations of 3-dimensional ventricles with a realistic His-Purkinje system were performed. Ventricles also included a dense scar or diffuse fibrosis.ResultsA finer spatial sampling produced better agreement with true CV. Using an error limit of 10 cm/s as a threshold, measurements taken within a region <2 cm from the pacing site proved to be accurate. Error increased abruptly beyond this distance. The Purkinje system and tissue fiber orientation played equally major roles in leading to a surface CV that was not reflective of the CV propagation through the tissue.ConclusionsIn general, surface CV correlates poorly with tissue CV. Only surface CV measurements close to the pacing site, taken with an electrode spacing of ≤1 mm, give reasonable estimates.
DOI: --
发表时间: 2023
期刊: Circulation
影响因子: 37.8
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T. Nishimura;Nathan Shatz;P. Weiss;M. Zawaneh;Rong Bai;Andrew D. Beaser;G. Upadhyay;Zaid A. Aziz;H. Nayak;Dalise Y. Shatz;S. Miyazaki;M. Goya;T. Sasano;W. Su;M. Raiman;Roderick Tung
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发表时间: 2021-12-23
影响因子: 7.7
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