Reduction of the nonspecific animal toxicity of anti-Tac(Fv)-PE38 by mutations in the framework regions of the Fv which lower the isoelectric point.

Reduction of the nonspecific animal toxicity of anti-Tac(Fv)-PE38 by mutations in the framework regions of the Fv which lower the isoelectric point.
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通过 Fv 框架区突变降低等电点,减少抗 Tac(Fv)-PE38 的非特异性动物毒性。

DOI:
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发表时间:
1999
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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通讯作者:
Pastan,I
Pastan,I
中科院分区:
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文献类型:
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作者:
Onda,M;Kreitman,RJ;Vasmatzis,G;Lee,B;Pastan,I

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