Egg retrieval with cryopreservation does not delay breast cancer treatment
Egg retrieval with cryopreservation does not delay breast cancer treatment
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DOI：
10.1016/j.amjsurg.2007.06.008
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发表时间：
2007-10-01
影响因子：
3
通讯作者：
Wapnir, Irene
中科院分区：
文献类型：
--
作者：
Madrigrano, Andrea;Westphal, Lynn;Wapnir, Irene
背景：不孕是年轻女性乳腺癌患者的一个问题。在生育技术的进步，使人们有可能银行受精embryos.Methods：23名妇女，年龄27至40岁，接受刺激/卵母细胞检索开始前的辅助治疗。结果：刺激至取卵的时间平均为11.5 d（9-20 d）。从第一次评估到取卵的平均时间间隔为33.3天（范围10-65天）。总体而言，从确定性手术到开始化疗的平均时间为46.8天（n = 20）。6例由外科医生转诊的患者，从生育咨询到取卵的平均时间为48.8 d（16-118 d），从确定性手术到开始化疗的平均时间为45 d（15-93 d）。由外科医生及早转诊给生育专家将有助于患者保障未来的生育。(c)2007 Excerpta Medica Inc. All rights reserved.
Background: Infertility is a concern to young women diagnosed with breast cancer. Advances in fertility technology have made it possible to bank fertilized embryos.Methods: Twenty-three women, ages 27 to 40 years, underwent stimulation/oocyte retrieval before the start of adjuvant therapies. Time intervals between retrieval and therapeutic procedures were analyzed.Results: The average stimulation to egg retrieval was 11.5 days (range 9-20 d). The average time interval from first evaluation to oocyte retrieval was 33.3 days (range 10-65 d). Overall, the mean time from definitive surgery to initiation of chemotherapy was 46.8 days (n = 20). For 6 patients referred by surgeons, the mean time from fertility consult to retrieval was 48.8 days (range 16-118 d), and from definitive surgery to initiation of chemotherapy was 45 days (range 15-93 d).Conclusions: Egg retrieval cryopreservation can be integrated with breast cancer work-up and surgical procedures. Early referrals to a fertility specialist by surgeons will help patients' safeguard future childbearing. (c) 2007 Excerpta Medica Inc. All rights reserved.