SARS-CoV-2 and HIV coinfection: clinical experience from Rhode Island, United States

SARS-CoV-2 and HIV coinfection: clinical experience from Rhode Island, United States
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DOI:
10.1002/jia2.25573
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发表时间:
2020-07-01
影响因子:
6
通讯作者:
Kantor, Rami
Kantor, Rami
中科院分区:
医学1区
文献类型:
--
作者:
Byrd, Katrina M.;Beckwith, Curt G.;Kantor, Rami

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简介 自 2019 年 12 月以来,严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 已感染全球超过 600 万人。全球关于 HIV/SARS-CoV-2 双重感染的报告有限。为了更好地了解 2019 年冠状病毒病 (COVID-19) 大流行对 HIV 感染者的影响并改善他们的护理,我们介绍了美国罗德岛州 HIV/SARS-CoV-2 合并感染的门诊和住院临床经验。方法 我们描述了门诊和住院患者对 COVID-19 大流行的准备情况,并介绍了美国罗德岛州普罗维登斯米里亚姆医院和罗德岛医院以及米里亚姆医院传染病和免疫学中心所有已知 HIV/SARS-CoV-2 双重感染患者的病例系列。结果和讨论 传染病和免疫学中心迅速为 HIV 和 SARS-CoV-2 感染者的门诊和住院治疗做好准备。 2020年3月30日至5月20日期间,27名艾滋病毒感染者被诊断出患有SARS-CoV-2。二十名男性、六名女性和一名跨性别女性;平均年龄49岁; 13/27 是西班牙裔,6/27 是非裔美国人。所有人都有 HIV 病毒载量
Introduction Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has infected >6 million people worldwide since December 2019. Global reports of HIV/SARS-CoV-2 coinfection are limited. To better understand the impact of the coronavirus disease 2019 (COVID-19) pandemic on persons with HIV and improve their care, we present an outpatient and inpatient clinical experience of HIV/SARS-CoV-2 coinfection from Rhode Island, US. Methods We describe outpatient and inpatient preparedness for the COVID-19 pandemic, and present a case series of all known patients with HIV/SARS-CoV-2 coinfection at The Miriam Hospital and Rhode Island Hospital, and The Miriam Hospital Infectious Diseases and Immunology Center, in Providence, Rhode Island, US. Results and discussion The Infectious Diseases and Immunology Center rapidly prepared for outpatient and inpatient care of persons with HIV and SARS-CoV-2. Between 30 March and 20 May 2020, 27 patients with HIV were diagnosed with SARS-CoV-2. Twenty were male, six female and one transgender female; average age was 49 years; 13/27 were Hispanic and 6/27 were African American. All had HIV viral load