Digital pathology. The time has come!
Digital pathology. The time has come!
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DOI：
10.1007/s00292-018-0431-0
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发表时间：
2018-05-01
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影响因子：
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通讯作者：
Grobholz, R.
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文献类型：
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作者：
Grobholz, R.
背景资料。数字病理学(DP)和全幻灯片成像(WSI)技术在过去几年中已经基本成熟。同时，可用于日常实践的商业系统也是可用的。例举了常规诊断环境中的DP经验。结果和结论。DP系统提供了几个优点：1)玻璃片不再是独一无二的；2)可以从任何位置访问病例；3)可以应用数字图像分析；以及4)可以很容易地访问存档的WSI。从这一点来看，出现了几个次要的优势：a)病例的幻灯片汇编和病例分配是快速和安全的；b)携带病例给病理学家是过时的，并且可以进行无纸化工作；c)WSI可以用于第二意见，并且可以在远程位置访问；d)在返回幻灯片之后仍然可以访问转诊病例的WSI；e)可以很容易地在肿瘤板中提供组织学图像；f)办公桌是干净的；以及g)可以是“家庭办公室”。为了引入发展规划系统，需要进行全面的工作流程分析，以阐明各研究所的需要和愿望。为了以最佳方式满足这些要求，开放式DP平台尤其具有优势，因为它们能够集成来自不同制造商的扫描仪。图像分析的进一步发展，如虚拟组织重建，可能会丰富未来的诊断过程，提高治疗质量。
Background. Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years. Meanwhile, commercial systems are available that can be used in routine practice.Aims. Illustration of DP experiences in a routine diagnostic setting.Results and Conclusions. A DP system offers several advantages: 1) glass slides are no longer unique; 2) access to cases is possible from any location; 3) digital image analysis can be applied; and 4) archived WSI can be easily accessed. From this point, several secondary advantages arise: a) the slide compilation of the case and the case assignment is fast and safe; b) carrying cases to the pathologist is obsolete and paperless work is possible; c) WSI can be used for a second opinion and be accessible in remote locations; d) WSI of referred cases are still accessible after returning the slides; e) histological images can easily be provided in tumor boards; f) the office desk is clean; and g) a "home office" is possible. To introduce a DP system, a comprehensive workflow analysis is needed that clarifies the needs and wishes of the respective institute. In order to optimally meet the requirements, open DP platforms are of particular advantage, because they enable the integration of scanners from various manufacturers. Further developments in image analysis, such as virtual tissue reconstruction, could enrich the diagnostic process in the future and improve treatment quality.