Odontogenic sarcoma and carcinosarcoma.
Odontogenic sarcoma and carcinosarcoma.
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牙源性肉瘤和癌肉瘤。
DOI：
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发表时间：
1999
影响因子：
2.3
通讯作者：
L. Slater
中科院分区：
文献类型：
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作者：
L. Slater
牙源性肉瘤是一种颌部恶性结缔组织肿瘤，其上皮与成釉细胞瘤或成釉细胞纤维瘤相似。它是一种混合性牙源性肿瘤，其中上皮成分是良性的，而增生的间叶成分是恶性的。随着每次复发，成釉细胞纤维肉瘤显示间质细胞和有丝分裂活性增加，但牙源性上皮减少。如果成釉细胞纤维肉瘤表现出发育不良的牙本质，它可以被称为成釉细胞纤维牙本质肉瘤，如果它还表现出发育不良的釉质蛋白的局灶性沉积，它可以被指定为成釉细胞纤维牙肉瘤。如果颌骨肿瘤同时具有癌性和恶性梭形细胞成分，且表现为成釉细胞纤维瘤样，则可称为牙源性癌肉瘤。如果缺乏这种类型，则应称之为“梭形细胞成釉细胞癌”或“双相成釉细胞肉瘤样癌”。这是美国政府的工作。其使用没有限制。
Odontogenic sarcoma is a gnathic malignant connective tissue tumor containing epithelium similar to that seen in an ameloblastoma or ameloblastic fibroma. It is a mixed odontogenic tumor in which the epithelial component is benign and the proliferative mesenchymal component is malignant. With each recurrence, the ameloblastic fibrosarcoma demonstrates increasing evidence of stromal cellularity and mitotic activity but diminishing evidence of odontogenic epithelium. If an ameloblastic fibrosarcoma exhibits dysplastic dentin, it can be called an ameloblastic fibrodentinosarcoma, and if it additionally shows focal deposits of dysplastic enamel proteins, it can be designated an ameloblastic fibro-odontosarcoma. A jaw tumor displaying both a carcinomatous and a malignant spindle cell component can be termed an odontogenic carcinosarcoma if it reveals an ameloblastic fibroma-like pattern. If it lacks this pattern, the appellations "spindle-cell ameloblastic carcinoma" or "biphasic ameloblastic sarcomatoid carcinoma" might be preferable. This is a US government work. There are no restrictions on its use.