Treatment of hantavirus pulmonary syndrome
Treatment of hantavirus pulmonary syndrome
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DOI：
10.1016/j.antiviral.2007.10.012
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发表时间：
2008-04-01
影响因子：
7.6
通讯作者：
Mertz, Gregory
中科院分区：
文献类型：
--
作者：
Jonsson, Colleen B.;Hooper, Jay;Mertz, Gregory
汉坦病毒属的病毒在从啮齿动物传播给人类时会导致两种严重疾病之一：肾综合征出血热（HFRS）或汉坦病毒肺综合征（HPS）。在这两种疾病中，HPS更严重，在美洲约有40%的死亡率。如果能发现有效的治疗方法，这种疾病的高死亡率可以降低。本文综述了HPS治疗方法的研究进展，以及HPS如何用于疾病的治疗和预防。(C)2007 Elsevier B.V.保留所有权利。
Viruses in the genus Hantavirus can cause one of two serious illnesses when transmitted from rodents to humans: hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). Of the two diseases, HPS is more severe with an approximate 40% mortality across the Americas. The high rate of mortality could be reduced if effective therapeutics could be discovered for treatment of this illness. Herein we review approaches being explored for the discovery of therapeutics for HPS and how they could be employed in treatment and preventiom of disease. (C) 2007 Elsevier B.V. All rights reserved.